Abstract
We present results of OCT and polarization-OCT applied to various ex vivo tissue samples and discuss related issues of image contrast, comparing in vivo and ex vivo preparations. Time-domain and frequency-domain OCT at 835nm and 1300nm have been applied to ex vivo skin and rabbit cornea. We can distinguish rabbit cornea epithelium for up to a month after excision. However, the skin loses all contrast upon excision and despite numerous experiments we cannot distinguish epidermis, which is clearly visible in vivo. Using a time-domain system, birefringence is clearly visible for decalcified tissue but can also be detected more weakly on fully mineralised tissue. Analysis suggests that demineralization increases the birefringence value.
Original language | English |
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Title of host publication | 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics |
Volume | 7139 |
DOIs | |
Publication status | Published - 30 Dec 2008 |
Event | 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics - Canterbury, Kent, United Kingdom Duration: 8 Sept 2008 → 10 Sept 2008 |
Conference
Conference | 1st Canterbury Workshop on Optical Coherence Tomography and Adaptive Optics |
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Country/Territory | United Kingdom |
City | Canterbury, Kent |
Period | 8/09/08 → 10/09/08 |
Keywords
- Ex vivo cornea
- Ex vivo skin
- Optical coherence tomography
- Tissue engineering
ASJC Scopus subject areas
- Applied Mathematics
- Computer Science Applications
- Electrical and Electronic Engineering
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics