Exploiting multimode waveguides for pure fibre-based imaging

Tomas Cizmar, Kishan Dholakia

    Research output: Contribution to journalArticlepeer-review

    371 Citations (Scopus)

    Abstract

    There has been an immense drive in modern microscopy towards miniaturization and fibre-based technology. This has been necessitated by the need to access hostile or difficult environments in situ and in vivo. Strategies to date have included the use of specialist fibres and miniaturized scanning systems accompanied by ingenious microfabricated lenses. Here we present a novel approach for this field by utilizing disordered light within a standard multimode optical fibre for lensless microscopy and optical mode conversion. We demonstrate the modalities of bright-and dark-field imaging and scanning fluorescence microscopy at acquisition rates that allow observation of dynamic processes such as Brownian motion of mesoscopic particles. Furthermore, we show how such control can realize a new form of mode converter and generate various types of advanced light fields such as propagation-invariant beams and optical vortices. These may be useful for future fibre-based implementations of super-resolution or light-sheet microscopy.

    Original languageEnglish
    Article numberARTN 1027
    Number of pages9
    JournalNature Communications
    Volume3
    Issue number1027
    DOIs
    Publication statusPublished - Aug 2012

    Keywords

    • RESOLUTION
    • DISORDERED MEDIA
    • TISSUES
    • ENDOSCOPE
    • PROPAGATION
    • LIGHT
    • MICROSCOPE
    • TRANSMISSION
    • IN-VIVO
    • BEAM

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