Extracellular vesicles: a new avenue for mRNA delivery

Shumei Wang; Paul R. J. Birch; Hailing Jin

doi:10.1016/j.tplants.2024.04.001

Extracellular vesicles: a new avenue for mRNA delivery

Shumei Wang (Lead / Corresponding author), Paul R. J. Birch, Hailing Jin (Lead / Corresponding author)

Plant Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Recent research reveals that plant mRNAs, packaged in extracellular vesicles, are delivered into fungal pathogen cells. Remarkably, the transferred mRNAs are translated by fungal ribosomes, generating functional proteins that impede infection. These findings offer new promising avenues to modify cellular performance by rapid delivery of mRNAs in plant-derived vesicles.

Original language	English
Pages (from-to)	845-847
Number of pages	3
Journal	Trends in Plant Science
Volume	29
Issue number	8
Early online date	13 Apr 2024
DOIs	https://doi.org/10.1016/j.tplants.2024.04.001
Publication status	Published - Aug 2024

Keywords

RNA trafficking
plant-microbe interactions
extracellular vesicles
cross-kingdom exchange
plant derived vesicles

ASJC Scopus subject areas

Plant Science

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10.1016/j.tplants.2024.04.001Licence: Elsevier User Licence

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Do Pathogen Exracellular Vesicles Deliver Crop Disease: PathEVome
Birch, P. (Investigator)
COMMISSION OF THE EUROPEAN COMMUNITIES
1/10/18 → 30/09/25
Project: Research
The Roles of Extracellular Vesicle Transport in Late Blight Disease Development (Industrial Partnership Award (IPA))
Birch, P. (Investigator)
Biotechnology and Biological Sciences Research Council
1/03/19 → 30/09/24
Project: Research

Cite this

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title = "Extracellular vesicles: a new avenue for mRNA delivery",

abstract = "Recent research reveals that plant mRNAs, packaged in extracellular vesicles, are delivered into fungal pathogen cells. Remarkably, the transferred mRNAs are translated by fungal ribosomes, generating functional proteins that impede infection. These findings offer new promising avenues to modify cellular performance by rapid delivery of mRNAs in plant-derived vesicles.",

keywords = "RNA trafficking, plant-microbe interactions, extracellular vesicles, cross-kingdom exchange, plant derived vesicles",

author = "Shumei Wang and Birch, {Paul R. J.} and Hailing Jin",

year = "2024",

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doi = "10.1016/j.tplants.2024.04.001",

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AU - Birch, Paul R. J.

AU - Jin, Hailing

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AB - Recent research reveals that plant mRNAs, packaged in extracellular vesicles, are delivered into fungal pathogen cells. Remarkably, the transferred mRNAs are translated by fungal ribosomes, generating functional proteins that impede infection. These findings offer new promising avenues to modify cellular performance by rapid delivery of mRNAs in plant-derived vesicles.

KW - RNA trafficking

KW - plant-microbe interactions

KW - extracellular vesicles

KW - cross-kingdom exchange

KW - plant derived vesicles

U2 - 10.1016/j.tplants.2024.04.001

DO - 10.1016/j.tplants.2024.04.001

M3 - Article

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EP - 847

JO - Trends in Plant Science

JF - Trends in Plant Science

IS - 8

ER -

Extracellular vesicles: a new avenue for mRNA delivery

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Embargoed Document

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Projects

Do Pathogen Exracellular Vesicles Deliver Crop Disease: PathEVome

The Roles of Extracellular Vesicle Transport in Late Blight Disease Development (Industrial Partnership Award (IPA))

Cite this