Fc receptors and immunity to parasites

Richard J. Pleass, Jenny M. Woof

Research output: Contribution to journalReview article

42 Citations (Scopus)

Abstract

Fc receptors (FcRs) are crucial in the immune system; they mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Parasites, in order to survive in the immunocompetent host, have devised ingenious methods to subvert this important aspect of the immune response. This article discusses the current thinking on FcRs, their role in immunity to parasites, and immune evasion strategies employed by parasites in their attempt to neutralize the important immune defense mechanisms mediated by these molecules.

Original languageEnglish
Pages (from-to)545-551
Number of pages7
JournalTrends in Parasitology
Volume17
Issue number11
DOIs
Publication statusPublished - 1 Nov 2001

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