TY - JOUR
T1 - Fc receptors and immunity to parasites
AU - Pleass, Richard J.
AU - Woof, Jenny M.
PY - 2001/11/1
Y1 - 2001/11/1
N2 - Fc receptors (FcRs) are crucial in the immune system; they mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Parasites, in order to survive in the immunocompetent host, have devised ingenious methods to subvert this important aspect of the immune response. This article discusses the current thinking on FcRs, their role in immunity to parasites, and immune evasion strategies employed by parasites in their attempt to neutralize the important immune defense mechanisms mediated by these molecules.
AB - Fc receptors (FcRs) are crucial in the immune system; they mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Parasites, in order to survive in the immunocompetent host, have devised ingenious methods to subvert this important aspect of the immune response. This article discusses the current thinking on FcRs, their role in immunity to parasites, and immune evasion strategies employed by parasites in their attempt to neutralize the important immune defense mechanisms mediated by these molecules.
UR - http://www.scopus.com/inward/record.url?scp=0035521240&partnerID=8YFLogxK
U2 - 10.1016/S1471-4922(01)02086-4
DO - 10.1016/S1471-4922(01)02086-4
M3 - Review article
C2 - 11872400
AN - SCOPUS:0035521240
VL - 17
SP - 545
EP - 551
JO - Trends in Parasitology
JF - Trends in Parasitology
SN - 1471-4922
IS - 11
ER -
