Feasibility study of using the dispersion of surface acoustic wave (SAW) impulse for viscoelasticity characterization in tissue mimicking phantoms

Kanheng Zhou, Chunhui Li (Lead / Corresponding author), Siping Chen, Ghulam Nabi, Zhihong Huang

Research output: Contribution to journalArticle

Abstract

The aim of this study was to investigate the feasibility of utilizing the phase velocity dispersion of impulse surface acoustic wave (SAW) for viscoelasticity characterization of soft materials. The focused ultrasound transducer and the phase sensitive optical coherence tomography (PhS-OCT) were applied as the impulse SAW inducer and tracker respectively. Three types of liquid-paraffin-based cream-in-agar phantoms were tested. Phase velocity dispersion curve was extracted using a Fourier transform based phase velocity analysis algorithm. Viscoelastic parameters were obtained by fitting the dispersion curve of SAW into Rayleigh wave dispersion equation. The estimated viscoelasticity was compared with that from spherical indenter, ramp-hold relaxation testing for validation. Both results show an increasing trend in the elasticity and decreasing trend in the viscosity with the concentration of liquid-paraffin-based cream increasing in the samples. The proposed method has the capability of evaluating the viscoelastic properties of homogeneous soft tissue. By combining viscoelastic parameters estimated from the proposed method, the dispersive-SAW-impulse-based viscosity compensated elastography could be further developed. This article is protected by copyright. All rights reserved.

Original languageEnglish
Article numbere201800177
Number of pages16
JournalJournal of Biophotonics
Early online date3 Aug 2018
DOIs
Publication statusE-pub ahead of print - 3 Aug 2018

Fingerprint

viscoelasticity
Viscoelasticity
Feasibility Studies
Surface waves
impulses
Phase velocity
phase velocity
Acoustic waves
Tissue
Mineral Oil
acoustics
paraffins
Viscosity
Paraffins
viscosity
trends
Elasticity Imaging Techniques
Rayleigh waves
Architectural Accessibility
wave dispersion

Keywords

  • viscoelasticity
  • impulse surface acoustic wave
  • dispersion
  • tissue mimicking phantoms
  • phase velocity
  • load-relaxation test

Cite this

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title = "Feasibility study of using the dispersion of surface acoustic wave (SAW) impulse for viscoelasticity characterization in tissue mimicking phantoms",
abstract = "The aim of this study was to investigate the feasibility of utilizing the phase velocity dispersion of impulse surface acoustic wave (SAW) for viscoelasticity characterization of soft materials. The focused ultrasound transducer and the phase sensitive optical coherence tomography (PhS-OCT) were applied as the impulse SAW inducer and tracker respectively. Three types of liquid-paraffin-based cream-in-agar phantoms were tested. Phase velocity dispersion curve was extracted using a Fourier transform based phase velocity analysis algorithm. Viscoelastic parameters were obtained by fitting the dispersion curve of SAW into Rayleigh wave dispersion equation. The estimated viscoelasticity was compared with that from spherical indenter, ramp-hold relaxation testing for validation. Both results show an increasing trend in the elasticity and decreasing trend in the viscosity with the concentration of liquid-paraffin-based cream increasing in the samples. The proposed method has the capability of evaluating the viscoelastic properties of homogeneous soft tissue. By combining viscoelastic parameters estimated from the proposed method, the dispersive-SAW-impulse-based viscosity compensated elastography could be further developed. This article is protected by copyright. All rights reserved.",
keywords = "viscoelasticity, impulse surface acoustic wave, dispersion, tissue mimicking phantoms, phase velocity, load-relaxation test",
author = "Kanheng Zhou and Chunhui Li and Siping Chen and Ghulam Nabi and Zhihong Huang",
note = "This article is protected by copyright. All rights reserved.",
year = "2018",
month = "8",
day = "3",
doi = "10.1002/jbio.201800177",
language = "English",
journal = "Journal of Biophotonics",
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T1 - Feasibility study of using the dispersion of surface acoustic wave (SAW) impulse for viscoelasticity characterization in tissue mimicking phantoms

AU - Zhou, Kanheng

AU - Li, Chunhui

AU - Chen, Siping

AU - Nabi, Ghulam

AU - Huang, Zhihong

N1 - This article is protected by copyright. All rights reserved.

PY - 2018/8/3

Y1 - 2018/8/3

N2 - The aim of this study was to investigate the feasibility of utilizing the phase velocity dispersion of impulse surface acoustic wave (SAW) for viscoelasticity characterization of soft materials. The focused ultrasound transducer and the phase sensitive optical coherence tomography (PhS-OCT) were applied as the impulse SAW inducer and tracker respectively. Three types of liquid-paraffin-based cream-in-agar phantoms were tested. Phase velocity dispersion curve was extracted using a Fourier transform based phase velocity analysis algorithm. Viscoelastic parameters were obtained by fitting the dispersion curve of SAW into Rayleigh wave dispersion equation. The estimated viscoelasticity was compared with that from spherical indenter, ramp-hold relaxation testing for validation. Both results show an increasing trend in the elasticity and decreasing trend in the viscosity with the concentration of liquid-paraffin-based cream increasing in the samples. The proposed method has the capability of evaluating the viscoelastic properties of homogeneous soft tissue. By combining viscoelastic parameters estimated from the proposed method, the dispersive-SAW-impulse-based viscosity compensated elastography could be further developed. This article is protected by copyright. All rights reserved.

AB - The aim of this study was to investigate the feasibility of utilizing the phase velocity dispersion of impulse surface acoustic wave (SAW) for viscoelasticity characterization of soft materials. The focused ultrasound transducer and the phase sensitive optical coherence tomography (PhS-OCT) were applied as the impulse SAW inducer and tracker respectively. Three types of liquid-paraffin-based cream-in-agar phantoms were tested. Phase velocity dispersion curve was extracted using a Fourier transform based phase velocity analysis algorithm. Viscoelastic parameters were obtained by fitting the dispersion curve of SAW into Rayleigh wave dispersion equation. The estimated viscoelasticity was compared with that from spherical indenter, ramp-hold relaxation testing for validation. Both results show an increasing trend in the elasticity and decreasing trend in the viscosity with the concentration of liquid-paraffin-based cream increasing in the samples. The proposed method has the capability of evaluating the viscoelastic properties of homogeneous soft tissue. By combining viscoelastic parameters estimated from the proposed method, the dispersive-SAW-impulse-based viscosity compensated elastography could be further developed. This article is protected by copyright. All rights reserved.

KW - viscoelasticity

KW - impulse surface acoustic wave

KW - dispersion

KW - tissue mimicking phantoms

KW - phase velocity

KW - load-relaxation test

U2 - 10.1002/jbio.201800177

DO - 10.1002/jbio.201800177

M3 - Article

JO - Journal of Biophotonics

JF - Journal of Biophotonics

SN - 1864-063X

M1 - e201800177

ER -