Feeding management before gastrointestinal studies in pigs

Rachael Gregson; Stephen Greenhalgh; Benjamin Cox; Sandy Cochrane; R. Eddie Clutton

doi:10.1177/0023677220960509

Feeding management before gastrointestinal studies in pigs

Rachael Gregson (Lead / Corresponding author), Stephen Greenhalgh, Benjamin Cox, Sandy Cochrane, R. Eddie Clutton

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

69 Downloads (Pure)

Abstract

Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.

Original language	English
Pages (from-to)	177-180
Number of pages	4
Journal	Laboratory Animals
Volume	55
Issue number	2
Early online date	12 Oct 2020
DOIs	https://doi.org/10.1177/0023677220960509
Publication status	Published - 1 Apr 2021

Keywords

Pigs
Anaesthesia
Food Withdrawal
Refinement
Gastrointestinal Tract
Capsule
Endoscopy
Colorectal Surgery
gastrointestinal tract
capsule endoscopy
food withdrawal
colorectal surgery
refinement
anaesthesia

ASJC Scopus subject areas

General Veterinary
Animal Science and Zoology

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10.1177/0023677220960509Licence: CC BY

Final Published VersionFinal published version, 251 KBLicence: CC BY

Cite this

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title = "Feeding management before gastrointestinal studies in pigs",

abstract = "Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.",

keywords = "Pigs, Anaesthesia, Food Withdrawal, Refinement, Gastrointestinal Tract, Capsule, Endoscopy, Colorectal Surgery, gastrointestinal tract, capsule endoscopy, food withdrawal, colorectal surgery, refinement, anaesthesia",

author = "Rachael Gregson and Stephen Greenhalgh and Benjamin Cox and Sandy Cochrane and Clutton, {R. Eddie}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: Funding from Wellcome Trust Biomedical Resource Grant to the Wellcome Trust Critical Care Laboratory for Large Animals (104972/Z/14/Z) and the UK Engineering and Physical Sciences Research Council (EPSRC) Sonopill grant (EP/K034537/2). Publisher Copyright: {\textcopyright} The Author(s) 2020.",

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doi = "10.1177/0023677220960509",

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AU - Gregson, Rachael

AU - Greenhalgh, Stephen

AU - Cox, Benjamin

AU - Cochrane, Sandy

AU - Clutton, R. Eddie

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: Funding from Wellcome Trust Biomedical Resource Grant to the Wellcome Trust Critical Care Laboratory for Large Animals (104972/Z/14/Z) and the UK Engineering and Physical Sciences Research Council (EPSRC) Sonopill grant (EP/K034537/2). Publisher Copyright: © The Author(s) 2020.

PY - 2021/4/1

Y1 - 2021/4/1

N2 - Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.

AB - Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.

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KW - Colorectal Surgery

KW - gastrointestinal tract

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KW - food withdrawal

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KW - refinement

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Feeding management before gastrointestinal studies in pigs

Abstract

Keywords

ASJC Scopus subject areas

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Sonopill: Minimally Invasive Gastrointestinal Diagnosis and Therapy (Joint with University of Glasgow & Heriot Watt University)

Cite this

Feeding management before gastrointestinal studies in pigs

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Projects

Sonopill: Minimally Invasive Gastrointestinal Diagnosis and Therapy (Joint with University of Glasgow & Heriot Watt University)

Cite this