Feeding management before gastrointestinal studies in pigs

Rachael Gregson (Lead / Corresponding author), Stephen Greenhalgh, Benjamin Cox, Sandy Cochrane, R. Eddie Clutton

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Abstract

Pigs are used to model humans in gastrointestinal (GI) studies because of their comparable size, physiology and behaviour: both are monogastric omnivores. A porcine surgical model for testing novel, tethered ultrasound capsule endoscopes (USCE) requires a clean, motile small intestine. Recommendations for human GI tract preparation before the mechanically similar process of video capsule endoscopy describe using oral purgatives, while high-carbohydrate drinks are recommended before colorectal surgery. Reports of the GI preparation of pigs exist but lack technical details, that is, administration, efficacy and side effects. This report details feeding a high-energy liquid diet to 11 female pigs undergoing surgery and USCE which was readily accepted and easily administered, and which produced a clean, motile small intestine and caused no detectable physiological/behavioural abnormalities.
Original languageEnglish
Number of pages4
JournalLaboratory Animals
Early online date12 Oct 2020
DOIs
Publication statusE-pub ahead of print - 12 Oct 2020

Keywords

  • Pigs
  • Anaesthesia
  • Food Withdrawal
  • Refinement
  • Gastrointestinal Tract
  • Capsule
  • Endoscopy
  • Colorectal Surgery
  • gastrointestinal tract
  • capsule endoscopy
  • food withdrawal
  • colorectal surgery
  • refinement
  • anaesthesia

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