Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children

M Kono (Lead / Corresponding author), M. Akiyama (Lead / Corresponding author), Y. Inoue, T. Nomura, A. Hata, Y. Okamoto, T. Takeichi, Y. Muro, W. H. I. McLean, H. Shimizu, K. Sugiura, Y. Suzuki, N. Shimojo

Research output: Contribution to journalLetter

3 Citations (Scopus)
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Abstract

Mutations in FLG are the underlying cause of ichthyosis vulgaris and are an important predisposing factor for atopic dermatitis (AD).1 In 2011, FLG mutations were reported to increase the risk of peanut allergy2 , and they have been proven to increase the risk of other food sensitizations and allergies.3,4 In this study, we comprehensively screened 411 children in Japan for 10 Japanese-population-specific FLG mutations and suggested that FLG mutations influence the persistence of food allergies (FAs). This article is protected by copyright. All rights reserved.

Original languageEnglish
Pages (from-to)190-191
Number of pages2
JournalBritish Journal of Dermatology
Volume179
Issue number1
Early online date25 Jan 2018
DOIs
Publication statusPublished - 19 Jul 2018

Keywords

  • Letter
  • Atopic dermatitis
  • Food allergy
  • Genetics
  • Filaggrin
  • FLG

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    Kono, M., Akiyama, M., Inoue, Y., Nomura, T., Hata, A., Okamoto, Y., Takeichi, T., Muro, Y., McLean, W. H. I., Shimizu, H., Sugiura, K., Suzuki, Y., & Shimojo, N. (2018). Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children. British Journal of Dermatology, 179(1), 190-191. https://doi.org/10.1111/bjd.16375