Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children

M Kono; M. Akiyama; Y. Inoue; T. Nomura; A. Hata; Y. Okamoto; T. Takeichi; Y. Muro; W. H. I. McLean; H. Shimizu; K. Sugiura; Y. Suzuki; N. Shimojo

doi:10.1111/bjd.16375

Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children

M Kono (Lead / Corresponding author), M. Akiyama (Lead / Corresponding author), Y. Inoue, T. Nomura, A. Hata, Y. Okamoto, T. Takeichi, Y. Muro, W. H. I. McLean, H. Shimizu, K. Sugiura, Y. Suzuki, N. Shimojo

Biological Chemistry and Drug Discovery

Research output: Contribution to journal › Letter › peer-review

7 Citations (Scopus)

305 Downloads (Pure)

Abstract

Mutations in FLG are the underlying cause of ichthyosis vulgaris and are an important predisposing factor for atopic dermatitis (AD).1 In 2011, FLG mutations were reported to increase the risk of peanut allergy2 , and they have been proven to increase the risk of other food sensitizations and allergies.3,4 In this study, we comprehensively screened 411 children in Japan for 10 Japanese-population-specific FLG mutations and suggested that FLG mutations influence the persistence of food allergies (FAs). This article is protected by copyright. All rights reserved.

Original language	English
Pages (from-to)	190-191
Number of pages	2
Journal	British Journal of Dermatology
Volume	179
Issue number	1
Early online date	25 Jan 2018
DOIs	https://doi.org/10.1111/bjd.16375
Publication status	Published - 19 Jul 2018

Keywords

Letter
Atopic dermatitis
Food allergy
Genetics
Filaggrin
FLG

ASJC Scopus subject areas

Dermatology

Access to Document

10.1111/bjd.16375

Author Accepted ManuscriptAccepted author manuscript, 235 KB

Cite this

@article{7111df7aa38c4948988301bc896a3c62,

title = "Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children",

abstract = "Mutations in FLG are the underlying cause of ichthyosis vulgaris and are an important predisposing factor for atopic dermatitis (AD).1 In 2011, FLG mutations were reported to increase the risk of peanut allergy2 , and they have been proven to increase the risk of other food sensitizations and allergies.3,4 In this study, we comprehensively screened 411 children in Japan for 10 Japanese-population-specific FLG mutations and suggested that FLG mutations influence the persistence of food allergies (FAs). This article is protected by copyright. All rights reserved.",

keywords = "Letter, Atopic dermatitis, Food allergy , Genetics, Filaggrin , FLG ",

author = "M Kono and M. Akiyama and Y. Inoue and T. Nomura and A. Hata and Y. Okamoto and T. Takeichi and Y. Muro and McLean, {W. H. I.} and H. Shimizu and K. Sugiura and Y. Suzuki and N. Shimojo",

note = "This work was supported in part by Grant-in-Aid for Scientific Research (A) 23249058 (to M.A.) and (C) 24591646 (to M.K.) from the Ministry of Education, Culture, Sports, Science and Technology of Japan",

year = "2018",

month = jul,

day = "19",

doi = "10.1111/bjd.16375",

language = "English",

volume = "179",

pages = "190--191",

journal = "British Journal of Dermatology",

issn = "0007-0963",

publisher = "Oxford University Press",

number = "1",

}

TY - JOUR

T1 - Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children

AU - Kono, M

AU - Akiyama, M.

AU - Inoue, Y.

AU - Nomura, T.

AU - Hata, A.

AU - Okamoto, Y.

AU - Takeichi, T.

AU - Muro, Y.

AU - McLean, W. H. I.

AU - Shimizu, H.

AU - Sugiura, K.

AU - Suzuki, Y.

AU - Shimojo, N.

N1 - This work was supported in part by Grant-in-Aid for Scientific Research (A) 23249058 (to M.A.) and (C) 24591646 (to M.K.) from the Ministry of Education, Culture, Sports, Science and Technology of Japan

PY - 2018/7/19

Y1 - 2018/7/19

N2 - Mutations in FLG are the underlying cause of ichthyosis vulgaris and are an important predisposing factor for atopic dermatitis (AD).1 In 2011, FLG mutations were reported to increase the risk of peanut allergy2 , and they have been proven to increase the risk of other food sensitizations and allergies.3,4 In this study, we comprehensively screened 411 children in Japan for 10 Japanese-population-specific FLG mutations and suggested that FLG mutations influence the persistence of food allergies (FAs). This article is protected by copyright. All rights reserved.

AB - Mutations in FLG are the underlying cause of ichthyosis vulgaris and are an important predisposing factor for atopic dermatitis (AD).1 In 2011, FLG mutations were reported to increase the risk of peanut allergy2 , and they have been proven to increase the risk of other food sensitizations and allergies.3,4 In this study, we comprehensively screened 411 children in Japan for 10 Japanese-population-specific FLG mutations and suggested that FLG mutations influence the persistence of food allergies (FAs). This article is protected by copyright. All rights reserved.

KW - Letter

KW - Atopic dermatitis

KW - Food allergy

KW - Genetics

KW - Filaggrin

KW - FLG

UR - http://www.scopus.com/inward/record.url?scp=85047529796&partnerID=8YFLogxK

U2 - 10.1111/bjd.16375

DO - 10.1111/bjd.16375

M3 - Letter

C2 - 29369340

SN - 0007-0963

VL - 179

SP - 190

EP - 191

JO - British Journal of Dermatology

JF - British Journal of Dermatology

IS - 1

ER -

Filaggrin gene mutations may influence the persistence of food allergies in Japanese primary school children

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this