Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency

Sanja Kezic, Grainne M. O'Regan, Rene Lutter, Ivone Jakasa, Ellen S. Koster, Sean Saunders, Peter Caspers, Patrick M. J. H. Kemperman, Gerwin J. Puppels, Aileen Sandilands, Huijia Chen, Linda E. Campbell, Karin Kroboth, Rosemarie Watson, Padraic G. Fallon, W. H. Irwin McLean, Alan D. Irvine

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    Medicine & Life Sciences