Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

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• Finished

  Strategic Award: Wellcome Trust Technology Platform

  Blow, J. (Investigator), Lamond, A. (Investigator) & Owen-Hughes, T. (Investigator)

  1/01/13 → 30/09/18

  Project: Research

  • Proteomics 100%
  • Ubiquitin 96%
  • Proteome 71%
  • Messenger RNA 59%
  • Chromatin 59%

• Dermatology and Genetic Medicine (Strategic Grant) (Joint with Kings College London)

  Barton, G. (Investigator), Campbell, P. (Investigator), Hickerson, R. (Investigator), Leigh, I. (Investigator), McLean, I. (Investigator) & Wyatt, P. (Investigator)

  1/08/12 → 30/04/19

  Project: Research

  • Atopic Dermatitis 100%
  • Palmoplantar Keratoderma 38%
  • Gain-of-function mutation 33%
  • Filaggrin 32%
  • Epidermis 29%