Abstract
Prevalent mutations in the FLG gene underlie the common skin disorder ichthyosis vulgaris and are significant risk factors for atopic dermatitis (eczema). The recent publication of a strategy to sequence this difficult gene identifies a spectrum of both prevalent and rare mutations that collectively have a significant impact on susceptibility to atopic disease.
Original language | English |
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Pages (from-to) | 1282-1284 |
Number of pages | 3 |
Journal | Journal of Investigative Dermatology |
Volume | 127 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2007 |
Keywords
- Dermatitis, Atopic
- Genetic Predisposition to Disease
- Humans
- Intermediate Filament Proteins
- Prevalence
- Risk Factors