Fluorescence image-guided surgery and repetitive Photodynamic Therapy in brain metastatic malignant melanoma

G. Zilidis; F. Aziz; S. Telara; M. Sam Eljamel

doi:10.1016/j.pdpdt.2009.01.001

Fluorescence image-guided surgery and repetitive Photodynamic Therapy in brain metastatic malignant melanoma

G. Zilidis, F. Aziz, S. Telara, M. Sam Eljamel

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Metastatic brain melanoma occurs in about 3.5% of patients suffering from malignant melanoma. It has disabling effects on cognition, memory, language and mobility. We studied the use of fluorescence image-guided resection and repetitive Photodynamic Therapy in six consecutive metastatic brain melanomas. Three were males and the mean age of the group was 52.8 years. Results: All six patients (100%) remained free of brain disease till death, 50% died of malignant melanoma elsewhere, and 50% died of unrelated causes. Conclusion: Adjuvant fluorescence image-guided resection and repetitive Photodynamic Therapy offers an excellent local control of metastatic brain melanoma. © 2009 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	264-266
Number of pages	3
Journal	Photodiagnosis and photodynamic therapy
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/j.pdpdt.2009.01.001
Publication status	Published - Dec 2008

Keywords

Adult
Aged, 80 and over
Brain Neoplasms
Dihematoporphyrin Ether
Female
Humans
Male
Melanoma
Middle Aged
Photochemotherapy
Photosensitizing Agents
Surgery, Computer-Assisted
Treatment Outcome

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10.1016/j.pdpdt.2009.01.001

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title = "Fluorescence image-guided surgery and repetitive Photodynamic Therapy in brain metastatic malignant melanoma",

abstract = "Metastatic brain melanoma occurs in about 3.5% of patients suffering from malignant melanoma. It has disabling effects on cognition, memory, language and mobility. We studied the use of fluorescence image-guided resection and repetitive Photodynamic Therapy in six consecutive metastatic brain melanomas. Three were males and the mean age of the group was 52.8 years. Results: All six patients (100%) remained free of brain disease till death, 50% died of malignant melanoma elsewhere, and 50% died of unrelated causes. Conclusion: Adjuvant fluorescence image-guided resection and repetitive Photodynamic Therapy offers an excellent local control of metastatic brain melanoma. {\textcopyright} 2009 Elsevier B.V. All rights reserved.",

keywords = "Adult, Aged, 80 and over, Brain Neoplasms, Dihematoporphyrin Ether, Female, Humans, Male, Melanoma, Middle Aged, Photochemotherapy, Photosensitizing Agents, Surgery, Computer-Assisted, Treatment Outcome",

author = "G. Zilidis and F. Aziz and S. Telara and Eljamel, {M. Sam}",

year = "2008",

month = dec,

doi = "10.1016/j.pdpdt.2009.01.001",

language = "English",

volume = "5",

pages = "264--266",

journal = "Photodiagnosis and Photodynamic Therapy",

issn = "1572-1000",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Fluorescence image-guided surgery and repetitive Photodynamic Therapy in brain metastatic malignant melanoma

AU - Zilidis, G.

AU - Aziz, F.

AU - Telara, S.

AU - Eljamel, M. Sam

PY - 2008/12

Y1 - 2008/12

N2 - Metastatic brain melanoma occurs in about 3.5% of patients suffering from malignant melanoma. It has disabling effects on cognition, memory, language and mobility. We studied the use of fluorescence image-guided resection and repetitive Photodynamic Therapy in six consecutive metastatic brain melanomas. Three were males and the mean age of the group was 52.8 years. Results: All six patients (100%) remained free of brain disease till death, 50% died of malignant melanoma elsewhere, and 50% died of unrelated causes. Conclusion: Adjuvant fluorescence image-guided resection and repetitive Photodynamic Therapy offers an excellent local control of metastatic brain melanoma. © 2009 Elsevier B.V. All rights reserved.

AB - Metastatic brain melanoma occurs in about 3.5% of patients suffering from malignant melanoma. It has disabling effects on cognition, memory, language and mobility. We studied the use of fluorescence image-guided resection and repetitive Photodynamic Therapy in six consecutive metastatic brain melanomas. Three were males and the mean age of the group was 52.8 years. Results: All six patients (100%) remained free of brain disease till death, 50% died of malignant melanoma elsewhere, and 50% died of unrelated causes. Conclusion: Adjuvant fluorescence image-guided resection and repetitive Photodynamic Therapy offers an excellent local control of metastatic brain melanoma. © 2009 Elsevier B.V. All rights reserved.

KW - Adult

KW - Aged, 80 and over

KW - Brain Neoplasms

KW - Dihematoporphyrin Ether

KW - Female

KW - Humans

KW - Male

KW - Melanoma

KW - Middle Aged

KW - Photochemotherapy

KW - Photosensitizing Agents

KW - Surgery, Computer-Assisted

KW - Treatment Outcome

U2 - 10.1016/j.pdpdt.2009.01.001

DO - 10.1016/j.pdpdt.2009.01.001

M3 - Article

C2 - 19356668

SN - 1572-1000

VL - 5

SP - 264

EP - 266

JO - Photodiagnosis and Photodynamic Therapy

JF - Photodiagnosis and Photodynamic Therapy

IS - 4

ER -

Fluorescence image-guided surgery and repetitive Photodynamic Therapy in brain metastatic malignant melanoma

Abstract

Keywords

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