Fluorescence image-guided surgery and repetitive Photodynamic Therapy in brain metastatic malignant melanoma

G. Zilidis, F. Aziz, S. Telara, M. Sam Eljamel

    Research output: Contribution to journalArticle

    24 Citations (Scopus)

    Abstract

    Metastatic brain melanoma occurs in about 3.5% of patients suffering from malignant melanoma. It has disabling effects on cognition, memory, language and mobility. We studied the use of fluorescence image-guided resection and repetitive Photodynamic Therapy in six consecutive metastatic brain melanomas. Three were males and the mean age of the group was 52.8 years. Results: All six patients (100%) remained free of brain disease till death, 50% died of malignant melanoma elsewhere, and 50% died of unrelated causes. Conclusion: Adjuvant fluorescence image-guided resection and repetitive Photodynamic Therapy offers an excellent local control of metastatic brain melanoma. © 2009 Elsevier B.V. All rights reserved.
    Original languageEnglish
    Pages (from-to)264-266
    Number of pages3
    JournalPhotodiagnosis and photodynamic therapy
    Volume5
    Issue number4
    DOIs
    Publication statusPublished - Dec 2008

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    Keywords

    • Adult
    • Aged, 80 and over
    • Brain Neoplasms
    • Dihematoporphyrin Ether
    • Female
    • Humans
    • Male
    • Melanoma
    • Middle Aged
    • Photochemotherapy
    • Photosensitizing Agents
    • Surgery, Computer-Assisted
    • Treatment Outcome

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