Fluorescence “Switch on” of Conjugates of CdTe@ZnS Quantum Dots with Al, Ni and Zn Tetraamino-Phthalocyanines by Hydrogen Peroxide: Characterization and Applications as Luminescent Nanosensors

Oluwasesan Adegoke, Samson Khene, Tebello Nyokong

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

In this study, we have developed a novel nanoprobe for H2O2 based on the conjugation of CdTe@ZnS quantum dots (QDs) to different metal tetraamino-phthalocyanine (MTAPc): (M = (OAc)Al, {OAc = acetate}, Ni and Zn). Chemical coordination of the QDs to the MTAPc resulted in the fluorescence "switch off" of the linked QDs which was associated with Förster resonance energy transfer (FRET). In the presence of varying concentration of H2O2, the fluorescence of the linked QDs was progressively "switched on" and the FRET mechanism between the QDs and the MTAPc was disrupted. The sensitivity/limit of detection of the nanoprobe followed the order: QDs-ZnTAPc (2.2 μM) > QDs-NiTAPc (4.4 μM) > QDs-AlTAPc (9.8 μM) while the selectivity followed the order: QDs-NiTAPc > QDs-AlTAPc > QDs-ZnTAPc. The varying degree of sensitivity/selectivity and mechanism of detection is discussed in detail.

Original languageEnglish
Pages (from-to)963-74
Number of pages12
JournalJournal of Fluorescence
Volume23
Issue number5
Early online date20 Apr 2013
DOIs
Publication statusPublished - Sep 2013

Fingerprint Dive into the research topics of 'Fluorescence “Switch on” of Conjugates of CdTe@ZnS Quantum Dots with Al, Ni and Zn Tetraamino-Phthalocyanines by Hydrogen Peroxide: Characterization and Applications as Luminescent Nanosensors'. Together they form a unique fingerprint.

  • Cite this