Fracture resistance of human roots filled with MTA mixed with phosphate‐buffered saline, with and without calcium hydroxide premedication

E. Zuk-Grajewska (Lead / Corresponding author), W. P. Saunders, R. G. Chadwick

Research output: Contribution to journalArticle

Abstract

Aim: To compare the fracture strength of extracted human roots with apical plugs of Mineral Trioxide Aggregate (MTA) mixed with either Ca‐ and Mg‐free phosphate‐buffered saline (PBS) or water, with and without calcium hydroxide (CH) premedication.

Methodology: A total of 180 single‐rooted human teeth were prepared to resemble immature roots and divided into groups (n = 20). The negative control received canal irrigation only, the positive control received treatment with CH for either two or twelve weeks. MTA mixed with water was used in Group 1: (i) without CH premedication ‐ MTA(W); (ii) after 2‐weeks CH premedication ‐ 2/52CH + MTA(W); (iii) after 12‐week CH premedication ‐ 12/52 CH + MTA(W). MTA mixed with PBS was used in Group 2: (i) without CH premedication ‐ MTA(PBS); (ii) after 2‐week CH premedication ‐ 2/52CH + MTA(PBS); (iii) after 12‐week CH premedication ‐ 12/52 CH + MTA(PBS). A compressive force was applied to each root until the point of fracture. The results were analysed by the Kruskal‐Wallis and Dunn’s multiple comparisons tests (P < 0.05).

Results: There was no significant difference between groups MTA(W), MTA(PBS) and 2/52CH + MTA(PBS), and all three groups were significantly (P < 0.01, P < 0.05, P < 0.05, respectively) more resistant to fracture than the negative control. Within Group 1, the samples that received two‐ (P < 0.01) and twelve‐ week (P < 0.001) CH pre‐treatment were more prone to fracture than those which did not. No difference was found among the control groups. The roots of the MTA(PBS) group had a higher dependability (P < 0.05) than the MTA(W) group when compared by the Weibull modulus. The difference was also present when a 2‐week CH premedication was used.

Conclusions: MTA mixed with Ca‐ and Mg‐free phosphate‐buffered saline had a significant strengthening effect on the fracture resistance of structurally weak roots, even when short‐term calcium hydroxide pre‐medication had been used. MTA mixed with water lost its strengthening effect on human roots when 2‐ or 12‐week CH pre‐treatment had been used. Use of CH dressing for up to 12 weeks had no negative effect on fracture resistance of human roots.
Original languageEnglish
JournalInternational Endodontic Journal
Early online date6 Oct 2020
DOIs
Publication statusE-pub ahead of print - 6 Oct 2020

Keywords

  • calcium hydroxide
  • fracture resistance
  • mineral trioxide aggregate
  • phosphate-buffered saline

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