Functional Amyloid and Other Protein Fibers in the Biofilm Matrix

Elliot Erskine, Cait E. MacPhee, Nicola Stanley-Wall (Lead / Corresponding author)

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Biofilms are ubiquitous in the natural and man-made environment. They are defined as microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing evidence from the genetic and biochemical analysis of single species biofilms has linked the presence of fibrous proteins to a functional biofilm matrix. Some of these fibers have been described as functional amyloid or amyloid-like fibers. Here we provide an overview of the biophysical and biological data for a wide range of protein fibers found in the biofilm matrix of Gram-positive and Gram-negative bacteria.

Original languageEnglish
Pages (from-to)3642-3656
Number of pages15
JournalJournal of Molecular Biology
Volume430
Issue number20
Early online date8 Aug 2018
DOIs
Publication statusPublished - 12 Oct 2018

Fingerprint

Amyloidogenic Proteins
Biofilms
Amyloid
Scleroproteins
Gram-Negative Bacteria
Molecular Biology
Proteins

Keywords

  • PSM
  • TasA
  • biofilm matrix
  • curli
  • functional amyloid fibers

Cite this

Erskine, Elliot ; MacPhee, Cait E. ; Stanley-Wall, Nicola. / Functional Amyloid and Other Protein Fibers in the Biofilm Matrix. In: Journal of Molecular Biology. 2018 ; Vol. 430, No. 20. pp. 3642-3656.
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Functional Amyloid and Other Protein Fibers in the Biofilm Matrix. / Erskine, Elliot; MacPhee, Cait E.; Stanley-Wall, Nicola (Lead / Corresponding author).

In: Journal of Molecular Biology, Vol. 430, No. 20, 12.10.2018, p. 3642-3656.

Research output: Contribution to journalReview article

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AU - MacPhee, Cait E.

AU - Stanley-Wall, Nicola

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