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Abstract
Biofilms are ubiquitous in the natural and man-made environment. They are defined as microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing evidence from the genetic and biochemical analysis of single species biofilms has linked the presence of fibrous proteins to a functional biofilm matrix. Some of these fibers have been described as functional amyloid or amyloid-like fibers. Here we provide an overview of the biophysical and biological data for a wide range of protein fibers found in the biofilm matrix of Gram-positive and Gram-negative bacteria.
Original language | English |
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Pages (from-to) | 3642-3656 |
Number of pages | 15 |
Journal | Journal of Molecular Biology |
Volume | 430 |
Issue number | 20 |
Early online date | 8 Aug 2018 |
DOIs | |
Publication status | Published - 12 Oct 2018 |
Keywords
- PSM
- TasA
- biofilm matrix
- curli
- functional amyloid fibers
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology
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Dive into the research topics of 'Functional Amyloid and Other Protein Fibers in the Biofilm Matrix'. Together they form a unique fingerprint.Student theses
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The structure and function of TasA in the Bacillus subtilis biofilm matrix
Author: Erskine, E., 2019Supervisor: Stanley-Wall, N. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy