Functional characterisation of the regulation of CAAT enhancer binding protein alpha by GSK-3 phosphorylation of Threonines 222/226

Keyphrases

• Phosphorylation 100%
• Glycogen Synthase Kinase 3 (GSK3) 100%
• Threonine 100%
• Functional Characterization 100%
• Enhancer-binding Protein 100%
• Alpha Activity 40%
• Insulin 20%
• Gene Promoter 20%
• Insulin-like Growth Factor Binding Protein (IGFBP) 20%
• Liver Cells 20%
• Response Element 20%
• Insulin Response 20%
• Thymine 20%
• Insulin Therapy 10%
• Gene Expression 10%
• Functional Outcome 10%
• Liver 10%
• Pharmacological Inhibitors 10%
• Hepatocytes 10%
• Adipocyte 10%
• Intact Cells 10%
• Glucose-6-phosphatase (G6Pase) 10%
• Phosphoenolpyruvate Carboxylase 10%
• 3T3-L1 Adipocytes 10%

Biochemistry, Genetics and Molecular Biology

• Binding Protein 100%
• GSK-3 100%
• CAAT Enhancer Binding 100%
• Threonine 100%
• Glycogen Synthase Kinase 3 81%
• Alpha Wave 36%
• Synapsin I 18%
• Response Element 18%
• Gene Promoter 18%
• Insulin Response 18%
• Alanine 18%
• Thymine 18%
• Gene Expression 9%
• Hepatocyte 9%
• Adipocyte 9%
• Glucose 6-Phosphatase 9%
• Phosphoenolpyruvate Carboxykinase 9%
• Preadipocyte 9%
• 3T3-L1 9%