Future prospects for the chemotherapy of human trypanosomiasis: 1. Novel approaches to the chemotherapy of trypanosomiasis

    Research output: Contribution to journalArticlepeer-review

    40 Citations (Scopus)

    Abstract

    Chemotherapy of trypanosomiasis and leishmaniasis is far from satisfactory and the discovery of new drugs has been slow. Emphasis on the empirical approach to drug development is now shifting towards a more rational, directed approach, which employs the modern tools of science. This is illustrated with respect to the newly discovered drug target, trypanothione, a unique metabolite which is critical for survival of Trypanosoma and Leishmania and absent from the host.

    Original languageEnglish
    Pages (from-to)613-617
    Number of pages5
    JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
    Volume84
    Issue number5
    DOIs
    Publication statusPublished - Sep 1990

    Fingerprint

    Dive into the research topics of 'Future prospects for the chemotherapy of human trypanosomiasis: 1. Novel approaches to the chemotherapy of trypanosomiasis'. Together they form a unique fingerprint.

    Cite this