Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology

Mark A. Baxter; Joana Marinho; Enrique Soto-Perez-de-Celis; Maria Grazia Rodriquenz; Sukeshi Patel Arora; Wendy Chan Wing Lok; Yung-Yu Shih; Gabor Liposits; Shane O'Hanlon; Russell D. Petty

doi:10.1016/j.jgo.2021.09.006

Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology

Mark A. Baxter (Lead / Corresponding author), Joana Marinho, Enrique Soto-Perez-de-Celis, Maria Grazia Rodriquenz, Sukeshi Patel Arora, Wendy Chan Wing Lok, Yung-Yu Shih, Gabor Liposits, Shane O'Hanlon, Russell D. Petty

Research output: Contribution to journal › Review article › peer-review

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Abstract

Gastroesophageal adenocarcinoma is a disease of older adults with very poor survival rates. Its incidence has risen dramatically across the world in recent decades. Current treatment approaches for older adults are based largely on extrapolated evidence from clinical trials conducted in younger and fitter participants than those more commonly encountered in clinical practice. Understanding how to apply available evidence to our patients in the clinic setting is essential given the high morbidity of both curative and palliative treatment. This review aims to use available data to inform the management of an older adult with gastroesophageal adenocarcinoma.

Original language	English
Pages (from-to)	7-19
Number of pages	13
Journal	Journal of Geriatric Oncology
Volume	13
Issue number	1
Early online date	18 Sept 2021
DOIs	https://doi.org/10.1016/j.jgo.2021.09.006
Publication status	Published - Jan 2022

Keywords

Frailty
Gastroesophageal adenocarcinoma
Multi-disciplinary
Real-world
Toxicity

ASJC Scopus subject areas

Oncology
Geriatrics and Gerontology

Access to Document

10.1016/j.jgo.2021.09.006Licence: Elsevier User Licence

Author Accepted ManuscriptAccepted author manuscript, 1.19 MBLicence: CC BY-NC-ND

Cite this

Baxter, M. A., Marinho, J., Soto-Perez-de-Celis, E., Rodriquenz, M. G., Arora, S. P., Lok, W. C. W., Shih, Y.-Y., Liposits, G., O'Hanlon, S., & Petty, R. D. (2022). Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology. Journal of Geriatric Oncology, 13(1), 7-19. https://doi.org/10.1016/j.jgo.2021.09.006

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title = "Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology",

abstract = "Gastroesophageal adenocarcinoma is a disease of older adults with very poor survival rates. Its incidence has risen dramatically across the world in recent decades. Current treatment approaches for older adults are based largely on extrapolated evidence from clinical trials conducted in younger and fitter participants than those more commonly encountered in clinical practice. Understanding how to apply available evidence to our patients in the clinic setting is essential given the high morbidity of both curative and palliative treatment. This review aims to use available data to inform the management of an older adult with gastroesophageal adenocarcinoma.",

keywords = "Frailty, Gastroesophageal adenocarcinoma, Multi-disciplinary, Real-world, Toxicity",

author = "Baxter, {Mark A.} and Joana Marinho and Enrique Soto-Perez-de-Celis and Rodriquenz, {Maria Grazia} and Arora, {Sukeshi Patel} and Lok, {Wendy Chan Wing} and Yung-Yu Shih and Gabor Liposits and Shane O'Hanlon and Petty, {Russell D.}",

note = "Dr. Baxter is a Clinical Academic Fellow funded by the Scottish Chief Scientist Office (CAF/20/01)",

year = "2022",

month = jan,

doi = "10.1016/j.jgo.2021.09.006",

language = "English",

volume = "13",

pages = "7--19",

journal = "Journal of Geriatric Oncology",

issn = "1879-4068",

publisher = "Elsevier",

number = "1",

}

Baxter, MA, Marinho, J, Soto-Perez-de-Celis, E, Rodriquenz, MG, Arora, SP, Lok, WCW, Shih, Y-Y, Liposits, G, O'Hanlon, S & Petty, RD 2022, 'Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology', Journal of Geriatric Oncology, vol. 13, no. 1, pp. 7-19. https://doi.org/10.1016/j.jgo.2021.09.006

Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology. / Baxter, Mark A. (Lead / Corresponding author); Marinho, Joana; Soto-Perez-de-Celis, Enrique et al.
In: Journal of Geriatric Oncology, Vol. 13, No. 1, 01.2022, p. 7-19.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Gastroesophageal adenocarcinoma in older adults

T2 - A comprehensive narrative review of management by the young international society of geriatric oncology

AU - Baxter, Mark A.

AU - Marinho, Joana

AU - Soto-Perez-de-Celis, Enrique

AU - Rodriquenz, Maria Grazia

AU - Arora, Sukeshi Patel

AU - Lok, Wendy Chan Wing

AU - Shih, Yung-Yu

AU - Liposits, Gabor

AU - O'Hanlon, Shane

AU - Petty, Russell D.

N1 - Dr. Baxter is a Clinical Academic Fellow funded by the Scottish Chief Scientist Office (CAF/20/01)

PY - 2022/1

Y1 - 2022/1

N2 - Gastroesophageal adenocarcinoma is a disease of older adults with very poor survival rates. Its incidence has risen dramatically across the world in recent decades. Current treatment approaches for older adults are based largely on extrapolated evidence from clinical trials conducted in younger and fitter participants than those more commonly encountered in clinical practice. Understanding how to apply available evidence to our patients in the clinic setting is essential given the high morbidity of both curative and palliative treatment. This review aims to use available data to inform the management of an older adult with gastroesophageal adenocarcinoma.

AB - Gastroesophageal adenocarcinoma is a disease of older adults with very poor survival rates. Its incidence has risen dramatically across the world in recent decades. Current treatment approaches for older adults are based largely on extrapolated evidence from clinical trials conducted in younger and fitter participants than those more commonly encountered in clinical practice. Understanding how to apply available evidence to our patients in the clinic setting is essential given the high morbidity of both curative and palliative treatment. This review aims to use available data to inform the management of an older adult with gastroesophageal adenocarcinoma.

KW - Frailty

KW - Gastroesophageal adenocarcinoma

KW - Multi-disciplinary

KW - Real-world

KW - Toxicity

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DO - 10.1016/j.jgo.2021.09.006

M3 - Review article

C2 - 34548259

SN - 1879-4068

VL - 13

SP - 7

EP - 19

JO - Journal of Geriatric Oncology

JF - Journal of Geriatric Oncology

IS - 1

ER -

Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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Identifying and Validating Predictive Biomarkers in Advanced Oesophagael Adenocarcinoma - A Springboard to REAListic Medicine (BE-REAL)

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Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the young international society of geriatric oncology

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Projects

Identifying and Validating Predictive Biomarkers in Advanced Oesophagael Adenocarcinoma - A Springboard to REAListic Medicine (BE-REAL)

Cite this