Gene activation at the edge of the nucleus

Jonathan R. Chubb

    Research output: Contribution to journalComment/debatepeer-review

    2 Citations (Scopus)

    Abstract

    The position of a gene within the nucleus can be a determinant of the level of gene activity. In recent years, particular emphasis has been placed on the nuclear envelope as a transcriptionally silent nuclear location. A provocative study on the relationship between nuclear architecture and transcription of the HIV provirus, published in this issue of The EMBO Journal, warrants a broader view.

    Original languageEnglish
    Pages (from-to)2145-2146
    Number of pages2
    JournalEMBO Journal
    Volume28
    Issue number15
    DOIs
    Publication statusPublished - 5 Aug 2009

    Keywords

    • Transcriptional competence
    • Chromatin
    • Periphery

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