Abstract
The position of a gene within the nucleus can be a determinant of the level of gene activity. In recent years, particular emphasis has been placed on the nuclear envelope as a transcriptionally silent nuclear location. A provocative study on the relationship between nuclear architecture and transcription of the HIV provirus, published in this issue of The EMBO Journal, warrants a broader view.
Original language | English |
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Pages (from-to) | 2145-2146 |
Number of pages | 2 |
Journal | EMBO Journal |
Volume | 28 |
Issue number | 15 |
DOIs |
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Publication status | Published - 5 Aug 2009 |
Keywords
- Transcriptional competence
- Chromatin
- Periphery