Research output per year
Research output per year
Million Veteran Program, Evangelos Evangelou, Helen R. Warren, David Mosen-Ansorena, Borbala Mifsud, Raha Pazoki, He Gao, Georgios Ntritsos, Niki Dimou, Claudia P. Cabrera, Ibrahim Karaman, Fu Liang Ng, Marina Evangelou, Katarzyna Witkowska, Evan Tzanis, Jacklyn N. Hellwege, Ayush Giri, Digna R. Velez Edwards, Yan V. Sun, Kelly Cho
Research output: Contribution to journal › Article › peer-review
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.
Original language | English |
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Pages (from-to) | 1412-1425 |
Number of pages | 14 |
Journal | Nature Genetics |
Volume | 50 |
Early online date | 17 Sep 2018 |
DOIs | |
Publication status | Published - Oct 2018 |
Research output: Contribution to journal › Article › peer-review
Person: Academic