Genetic and structural validation of phosphomannomutase as a cell wall target in Aspergillus fumigatus

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• Finished

  Inhibition by Proxy Targeting Fungal Citin Synthesis through Sugar Nucleotide Biosynthesis (Clinical Postdoctoral Research Training Fellowship)

  Lockhart, D. & van Aalten, D.

  Wellcome Trust

  1/12/15 → 31/05/18

  Project: Research

  • Cell Wall 100%
  • Aspergillus fumigatus 73%
  • phosphomannomutase 57%
  • Hexosamine 46%
  • Hexosamines 46%

• Genetic Structural and Chemical Validation of Aspergillus Fumigatus Cell Wall Targets (Programme Grant)

  van Aalten, D.

  Medical Research Council

  1/11/14 → 31/10/19

  Project: Research

  • Aspergillus fumigatus 100%
  • Cell Wall 81%
  • Chitin 64%
  • glycylpeptide N-tetradecanoyltransferase 51%
  • Enzymes 51%