Abstract
Genetic background has a major influence on the manifestation of multifactorial diseases such as hypertension in which severe complications may be caused through an interaction with additional factors, which may be genetically determined. We have previously described a genetic model of malignant hypertension (MH) in rats carrying the mouse Ren2 gene (TGRmRen2-27), in which the phenotype is dependent on the genetic background.
Original language | English |
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Pages (from-to) | 414-20 |
Number of pages | 7 |
Journal | Kidney International |
Volume | 56 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1999 |