@article{91053c0fdbbf432c9f896ceda91c3672,
title = "Genome sequence and analysis of the tuber crop potato",
abstract = "Potato (Solanum tuberosum L.) is the world's most important non-grain food crop and is central to global food security. It is clonally propagated, highly heterozygous, autotetraploid, and suffers acute inbreeding depression. Here we use a homozygous doubled-monoploid potato clone to sequence and assemble 86% of the 844-megabase genome. We predict 39,031 protein-coding genes and present evidence for at least two genome duplication events indicative of a palaeopolyploid origin. As the first genome sequence of an asterid, the potato genome reveals 2,642 genes specific to this large angiosperm clade. We also sequenced a heterozygous diploid clone and show that gene presence/absence variants and other potentially deleterious mutations occur frequently and are a likely cause of inbreeding depression. Gene family expansion, tissue-specific expression and recruitment of genes to new pathways contributed to the evolution of tuber development. The potato genome sequence provides a platform for genetic improvement of this vital crop.",
author = "{The Potato Genome Sequencing Consortium} and Xun Xu and Shengkai Pan and Shifeng Cheng and Bo Zhang and Desheng Mu and Peixiang Ni and Gengyun Zhang and Shuang Yang and Ruiqiang Li and Jun Wang and Gisella Orjeda and Frank Guzman and Michael Torres and Roberto Lozano and Olga Ponce and Diana Martinez and {De La Cruz}, Germ{\'a}n and Chakrabarti, {S. K.} and Patil, {Virupaksh U.} and Skryabin, {Konstantin G.} and Kuznetsov, {Boris B.} and Ravin, {Nikolai V.} and Kolganova, {Tatjana V.} and Beletsky, {Alexey V.} and Mardanov, {Andrei V.} and {Di Genova}, Alex and Bolser, {Daniel M.} and Martin, {David M.A.} and Guangcun Li and Yu Yang and Hanhui Kuang and Qun Hu and Xingyao Xiong and Bishop, {Gerard J.} and Boris Sagredo and Nilo Mej{\'i}a and Wlodzimierz Zagorski and Robert Gromadka and Jan Gawor and Pawel Szczesny and Sanwen Huang and Zhonghua Zhang and Chunbo Liang and Jun He and Sharma, {Sanjeev Kumar} and Marshall, {David F.} and Robbie Waugh and Bryan, {Glenn J.} and Dan Milbourne and Thomson, {Susan J.}",
year = "2011",
month = jul,
day = "14",
doi = "10.1038/nature10158",
language = "English",
volume = "475",
pages = "189--195",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7355",
}