Genome sequence and analysis of the tuber crop potato

TY - JOUR

T1 - Genome sequence and analysis of the tuber crop potato

AU - The Potato Genome Sequencing Consortium

AU - Xu, Xun

AU - Pan, Shengkai

AU - Cheng, Shifeng

AU - Zhang, Bo

AU - Mu, Desheng

AU - Ni, Peixiang

AU - Zhang, Gengyun

AU - Yang, Shuang

AU - Li, Ruiqiang

AU - Wang, Jun

AU - Orjeda, Gisella

AU - Guzman, Frank

AU - Torres, Michael

AU - Lozano, Roberto

AU - Ponce, Olga

AU - Martinez, Diana

AU - De La Cruz, Germán

AU - Chakrabarti, S. K.

AU - Patil, Virupaksh U.

AU - Skryabin, Konstantin G.

AU - Kuznetsov, Boris B.

AU - Ravin, Nikolai V.

AU - Kolganova, Tatjana V.

AU - Beletsky, Alexey V.

AU - Mardanov, Andrei V.

AU - Di Genova, Alex

AU - Bolser, Daniel M.

AU - Martin, David M.A.

AU - Li, Guangcun

AU - Yang, Yu

AU - Kuang, Hanhui

AU - Hu, Qun

AU - Xiong, Xingyao

AU - Bishop, Gerard J.

AU - Sagredo, Boris

AU - Mejía, Nilo

AU - Zagorski, Wlodzimierz

AU - Gromadka, Robert

AU - Gawor, Jan

AU - Szczesny, Pawel

AU - Huang, Sanwen

AU - Zhang, Zhonghua

AU - Liang, Chunbo

AU - He, Jun

AU - Sharma, Sanjeev Kumar

AU - Marshall, David F.

AU - Waugh, Robbie

AU - Bryan, Glenn J.

AU - Milbourne, Dan

AU - Thomson, Susan J.

PY - 2011/7/14

Y1 - 2011/7/14

N2 - Potato (Solanum tuberosum L.) is the world's most important non-grain food crop and is central to global food security. It is clonally propagated, highly heterozygous, autotetraploid, and suffers acute inbreeding depression. Here we use a homozygous doubled-monoploid potato clone to sequence and assemble 86% of the 844-megabase genome. We predict 39,031 protein-coding genes and present evidence for at least two genome duplication events indicative of a palaeopolyploid origin. As the first genome sequence of an asterid, the potato genome reveals 2,642 genes specific to this large angiosperm clade. We also sequenced a heterozygous diploid clone and show that gene presence/absence variants and other potentially deleterious mutations occur frequently and are a likely cause of inbreeding depression. Gene family expansion, tissue-specific expression and recruitment of genes to new pathways contributed to the evolution of tuber development. The potato genome sequence provides a platform for genetic improvement of this vital crop.

AB - Potato (Solanum tuberosum L.) is the world's most important non-grain food crop and is central to global food security. It is clonally propagated, highly heterozygous, autotetraploid, and suffers acute inbreeding depression. Here we use a homozygous doubled-monoploid potato clone to sequence and assemble 86% of the 844-megabase genome. We predict 39,031 protein-coding genes and present evidence for at least two genome duplication events indicative of a palaeopolyploid origin. As the first genome sequence of an asterid, the potato genome reveals 2,642 genes specific to this large angiosperm clade. We also sequenced a heterozygous diploid clone and show that gene presence/absence variants and other potentially deleterious mutations occur frequently and are a likely cause of inbreeding depression. Gene family expansion, tissue-specific expression and recruitment of genes to new pathways contributed to the evolution of tuber development. The potato genome sequence provides a platform for genetic improvement of this vital crop.

UR - https://www.scopus.com/pages/publications/79960422847

U2 - 10.1038/nature10158

DO - 10.1038/nature10158

M3 - Article

C2 - 21743474

AN - SCOPUS:79960422847

SN - 0028-0836

VL - 475

SP - 189

EP - 195

JO - Nature

JF - Nature

IS - 7355

ER -