TY - JOUR
T1 - Genome-wide association analysis of grain yield-associated traits in a pan-European barley cultivar collection
AU - Xu, Xin
AU - Sharma, Rajiv
AU - Tondelli, Allessandro
AU - Russell, Joanne
AU - Comadran, Jordi
AU - Pillen, Klaus
AU - Schnaithmann, Florian
AU - Kilian, Benjamin
AU - Cattivelli, Luigi
AU - Thomas, William T. B.
AU - Flavell, Andrew J.
N1 - This work was supported by ERA-PG-funded project Exbardiv (Genomics-Assisted Analysis and Exploitation of Barley Diversity; http://www.erapg.org) and ERA-CAPS project Barley-NAM (Locating exotic genes that control agronomic traits under stress in a wild barley nested association mapping (NAM) population; http://www.eracaps.org). We thank the following persons for excellent technical assistance: Hazel Bull, Birgit Dubsky, Nadia Faccini, Heike Harms, Christiane Kehler, Richard Keith, Ute Krajewski, Leena Lohermaa, Marja-Leena Manninen, Marita Nix, Donata Pagani, Peter Schreiber, Kerstin Wolf, and the “Experimental Fields and Nurseries” and “Genome Diversity” group at IPK. We are also grateful to the following for support and discussions: Christine Hackett, Andreas Graner, Raj K. Pasam, Kerstin Neumann, and Michele Stanca. The authors declare no conflicts of interest.
PY - 2018/1/25
Y1 - 2018/1/25
N2 - A collection of 379 Hordeum vulgare cultivars, comprising all combinations of spring and winter growth habits with 2 and 6 row ear type, was screened by genome wide association analysis to discover alleles controlling traits related to grain yield. Genotypes were obtained at 6810 segregating gene-based SNP loci and corresponding field trial data were obtained for ten traits related to grain yield at four European sites in three countries over two growth years. The combined data were analysed and statistically significant associations between the traits and regions of the barley genomes were obtained. Combining this information with the high resolution gene map for barley allowed the identification of candidate genes underlying all scored traits and superposition of this information with the known genomics of grain trait genes in rice resulted in the assignation of 13 putative barley genes controlling grain traits in European cultivated barley. Several of these genes are associated with grain traits in both winter and spring barley.
AB - A collection of 379 Hordeum vulgare cultivars, comprising all combinations of spring and winter growth habits with 2 and 6 row ear type, was screened by genome wide association analysis to discover alleles controlling traits related to grain yield. Genotypes were obtained at 6810 segregating gene-based SNP loci and corresponding field trial data were obtained for ten traits related to grain yield at four European sites in three countries over two growth years. The combined data were analysed and statistically significant associations between the traits and regions of the barley genomes were obtained. Combining this information with the high resolution gene map for barley allowed the identification of candidate genes underlying all scored traits and superposition of this information with the known genomics of grain trait genes in rice resulted in the assignation of 13 putative barley genes controlling grain traits in European cultivated barley. Several of these genes are associated with grain traits in both winter and spring barley.
KW - Europe
KW - Genome-Wide Association Study
KW - Genotype
KW - Hordeum/genetics
KW - Plant Proteins/genetics
KW - Polymorphism, Single Nucleotide
KW - Quantitative Trait Loci
KW - Seeds/genetics
UR - http://www.scopus.com/inward/record.url?scp=85043763180&partnerID=8YFLogxK
U2 - 10.3835/plantgenome2017.08.0073
DO - 10.3835/plantgenome2017.08.0073
M3 - Article
C2 - 29505630
SN - 1940-3372
VL - 11
SP - 1
EP - 11
JO - Plant Genome
JF - Plant Genome
IS - 1
M1 - 170073
ER -