Genomic data of an environmental Escherichia coli isolate shows high resemblance to E. coli K-12 reference strain MG1655

Nicola Holden (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

3 Downloads (Pure)


Escherichia coli species exhibits a high genomic diversification from evolution, mobile genetic elements and recombination. An environmental E. coli isolate, ‘JHI_5025’ from a crop trial appeared to be clonally related to the historical reference isolate E. coli K-12 strain ‘MG1655’, warranting further genomic analysis. Their genomes share an average nucleotide identity of 99.74% and whole genome alignment showed little rearrangement of the JHI_5025 sequence compared to the reference. Five genomic islands not in the reference aligned to other sequences in the Enterobacteriaceae. Isolate JHI_5025 contained E. coli K-12 F plasmid sequence and at least one complete prophage sequence. The genome and comparison dataset provides utility of E. coli JHI_5025 as a representative contemporary genetic mimic of a well-known and much used workhorse strain.

Original languageEnglish
Article number107586
Number of pages6
JournalData in Brief
Early online date18 Nov 2021
Publication statusPublished - Dec 2021


  • Clonality
  • Phylogenomics
  • Whole genome alignment
  • Whole genome sequencing


Dive into the research topics of 'Genomic data of an environmental <i>Escherichia coli</i> isolate shows high resemblance to <i>E. col</i>i K-12 reference strain MG1655'. Together they form a unique fingerprint.

Cite this