Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2+/CaMKK2 Signaling to Enhance Tumor Cell Survival

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• Finished

  Rab Detection Initiative (Joint with Stanford School of Medicine, Max Plank Institute, Neuroscience Research Australia and Parkinsons Institute California)

  Alessi, D. & Davies, P.

  1/08/16 → 31/07/21

  Project: Research

  • AMP-Activated Protein Kinases 100%
  • Adenosine Monophosphate 21%
  • Adenosine Triphosphate 16%
  • Metformin 15%
  • Neoplasms 15%

• AMP-Activated Protein Kinase - A Tumour Suppressor that Opposes the Metabolic Changes in Proliferating Cells (Programme Grant)

  Hardie, G.

  Cancer Research UK

  1/01/13 → 30/09/18

  Project: Research

  • AMP-Activated Protein Kinases 100%
  • Adenosine Monophosphate 33%
  • Adenosine Triphosphate 23%
  • Phenformin 22%
  • adenosine monophosphate 21%

• Non-canonical Pathways for Regulation of AMPK (Senior Investigator Award)

  Hardie, G.

  Wellcome Trust

  1/04/12 → 30/09/17

  Project: Research

  • AMP-Activated Protein Kinases 100%
  • Adenosine Monophosphate 34%
  • Adenosine Triphosphate 17%
  • Metformin 16%
  • Phosphorylation 15%