Gluconeogenesis in plants: A key interface between organic acid/amino Acid/Lipid and sugar metabolism

Robert P. Walker; Zhi Hui Chen; Franco Famiani

doi:10.3390/molecules26175129

Gluconeogenesis in plants: A key interface between organic acid/amino Acid/Lipid and sugar metabolism

Robert P. Walker (Lead / Corresponding author), Zhi Hui Chen (Lead / Corresponding author), Franco Famiani (Lead / Corresponding author)

Research output: Contribution to journal › Review article › peer-review

52 Citations (Scopus)

184 Downloads (Pure)

Abstract

The aims of this article are four‐fold. First, to provide a concise overview of plant gluconeogenesis. Second, to emphasise the widespread occurrence of gluconeogenesis and its utilisation in diverse processes. Third, to stress the importance of the vacuolar storage and release of Krebs cycle acids/nitrogenous compounds; and of the role of gluconeogenesis and malic enzyme in this process. Fourth, to outline the contribution of fine control of enzyme activity to the coordinate‐regulation of gluconeogenesis and malate metabolism; and the importance of cytosolic pH in this.

Original language	English
Article number	5129
Number of pages	18
Journal	Molecules
Volume	26
Issue number	17
DOIs	https://doi.org/10.3390/molecules26175129
Publication status	Published - 24 Aug 2021

Keywords

Gluconeogenesis
Malate
Malic enzyme
Nitrogen metabolism
Organic acids
Phosphoenolpyruvate carboxykinase
Pyruvate orthophosphate dikinase
Vacuole

ASJC Scopus subject areas

Analytical Chemistry
Chemistry (miscellaneous)
Molecular Medicine
Pharmaceutical Science
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry

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10.3390/molecules26175129Licence: CC BY

Final Published VersionFinal published version, 7.4 MBLicence: CC BY

Cite this

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title = "Gluconeogenesis in plants: A key interface between organic acid/amino Acid/Lipid and sugar metabolism",

abstract = "The aims of this article are four‐fold. First, to provide a concise overview of plant gluconeogenesis. Second, to emphasise the widespread occurrence of gluconeogenesis and its utilisation in diverse processes. Third, to stress the importance of the vacuolar storage and release of Krebs cycle acids/nitrogenous compounds; and of the role of gluconeogenesis and malic enzyme in this process. Fourth, to outline the contribution of fine control of enzyme activity to the coordinate‐regulation of gluconeogenesis and malate metabolism; and the importance of cytosolic pH in this.",

keywords = "Gluconeogenesis, Malate, Malic enzyme, Nitrogen metabolism, Organic acids, Phosphoenolpyruvate carboxykinase, Pyruvate orthophosphate dikinase, Vacuole",

author = "Walker, {Robert P.} and Chen, {Zhi Hui} and Franco Famiani",

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language = "English",

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Gluconeogenesis in plants: A key interface between organic acid/amino Acid/Lipid and sugar metabolism. / Walker, Robert P. (Lead / Corresponding author); Chen, Zhi Hui (Lead / Corresponding author); Famiani, Franco (Lead / Corresponding author).
In: Molecules, Vol. 26, No. 17, 5129, 24.08.2021.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Gluconeogenesis in plants

T2 - A key interface between organic acid/amino Acid/Lipid and sugar metabolism

AU - Walker, Robert P.

AU - Chen, Zhi Hui

AU - Famiani, Franco

PY - 2021/8/24

Y1 - 2021/8/24

N2 - The aims of this article are four‐fold. First, to provide a concise overview of plant gluconeogenesis. Second, to emphasise the widespread occurrence of gluconeogenesis and its utilisation in diverse processes. Third, to stress the importance of the vacuolar storage and release of Krebs cycle acids/nitrogenous compounds; and of the role of gluconeogenesis and malic enzyme in this process. Fourth, to outline the contribution of fine control of enzyme activity to the coordinate‐regulation of gluconeogenesis and malate metabolism; and the importance of cytosolic pH in this.

AB - The aims of this article are four‐fold. First, to provide a concise overview of plant gluconeogenesis. Second, to emphasise the widespread occurrence of gluconeogenesis and its utilisation in diverse processes. Third, to stress the importance of the vacuolar storage and release of Krebs cycle acids/nitrogenous compounds; and of the role of gluconeogenesis and malic enzyme in this process. Fourth, to outline the contribution of fine control of enzyme activity to the coordinate‐regulation of gluconeogenesis and malate metabolism; and the importance of cytosolic pH in this.

KW - Gluconeogenesis

KW - Malate

KW - Malic enzyme

KW - Nitrogen metabolism

KW - Organic acids

KW - Phosphoenolpyruvate carboxykinase

KW - Pyruvate orthophosphate dikinase

KW - Vacuole

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U2 - 10.3390/molecules26175129

DO - 10.3390/molecules26175129

M3 - Review article

C2 - 34500562

AN - SCOPUS:85113600049

SN - 1420-3049

VL - 26

JO - Molecules

JF - Molecules

IS - 17

M1 - 5129

ER -

Gluconeogenesis in plants: A key interface between organic acid/amino Acid/Lipid and sugar metabolism

Abstract

Keywords

ASJC Scopus subject areas

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