Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus

D. C. Sharman; A. D. Morris; A. D. Struthers

doi:10.1007/s00125-007-0754-5

Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus

D. C. Sharman, A. D. Morris, A. D. Struthers

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Abstract

In chronic heart failure there is gradual reactivation of vascular tissue angiotensin I (AI) to angiotensin II (AII) conversion over time in patients taking chronic ACE inhibitor therapy. However, it remains unknown whether the same overall phenomenon occurs in other patients taking chronic ACE inhibitor therapy, such as patients with type 2 diabetes mellitus.

Original language	English
Pages (from-to)	2061-2066
Number of pages	6
Journal	Diabetologia
Volume	50
Issue number	10
DOIs	https://doi.org/10.1007/s00125-007-0754-5
Publication status	Published - Oct 2007

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title = "Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus",

abstract = "In chronic heart failure there is gradual reactivation of vascular tissue angiotensin I (AI) to angiotensin II (AII) conversion over time in patients taking chronic ACE inhibitor therapy. However, it remains unknown whether the same overall phenomenon occurs in other patients taking chronic ACE inhibitor therapy, such as patients with type 2 diabetes mellitus.",

author = "Sharman, {D. C.} and Morris, {A. D.} and Struthers, {A. D.}",

year = "2007",

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AU - Morris, A. D.

AU - Struthers, A. D.

PY - 2007/10

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N2 - In chronic heart failure there is gradual reactivation of vascular tissue angiotensin I (AI) to angiotensin II (AII) conversion over time in patients taking chronic ACE inhibitor therapy. However, it remains unknown whether the same overall phenomenon occurs in other patients taking chronic ACE inhibitor therapy, such as patients with type 2 diabetes mellitus.

AB - In chronic heart failure there is gradual reactivation of vascular tissue angiotensin I (AI) to angiotensin II (AII) conversion over time in patients taking chronic ACE inhibitor therapy. However, it remains unknown whether the same overall phenomenon occurs in other patients taking chronic ACE inhibitor therapy, such as patients with type 2 diabetes mellitus.

U2 - 10.1007/s00125-007-0754-5

DO - 10.1007/s00125-007-0754-5

M3 - Article

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SN - 0012-186X

VL - 50

SP - 2061

EP - 2066

JO - Diabetologia

JF - Diabetologia

IS - 10

ER -

Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus

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