Abstract
Cell-permeable chemical inhibitors have become invaluable reagents for the study of cellular regulation. In the present paper, using protein kinase inhibitors as the example, a set of criteria are described that should be met before any investigation using such compounds should be accepted for publication.
Original language | English |
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Pages (from-to) | 53-54 |
Number of pages | 2 |
Journal | Biochemical Journal |
Volume | 425 |
DOIs | |
Publication status | Published - 1 Jan 2010 |
Keywords
- cell regulation
- chemical biology
- chemical inhibitor
- protein kinase
- signal transduction
- KINASE INHIBITORS
- IN-VIVO
- SPECIFICITY
- UPDATE