Guidelines on the management of secondary prophylaxis of vascular events in stable patients in primary care

D J Betteridge, J Belch, M. M. Brown, M Gent, D Julian, S Long, S Morris, J Pittard, M Pye

    Research output: Contribution to journalArticle

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    Abstract

    Atherothrombosis, thrombus formation superimposed on an existing atherosclerotic plaque, is an acute process leading to ischaemic events such as myocardial infarction, stroke and critical limb ischaemia. Patients presenting with clinical conditions associated with atherothrombosis are at increased risk of subsequent vascular events. The beneficial effect of antiplatelet therapies for short-term and long-term secondary prevention of atherothrombotic events has been established. These guidelines aim to provide evidence-based recommendations that will assist in the antiplatelet-mediated secondary prophylaxis of vascular events in patients with stable cardiovascular disease treated in the primary healthcare setting. Medline and the Cochrane library were accessed using free-text strategies in the domains of antiplatelet agents and antithrombotics. Development of the guidelines was driven by a series of Steering Committee meetings, in which the quality of relevant studies was assessed and identified using narrative summary. These guidelines present evidence and recommendations for the treatment of numerous atherothrombotic indications depending on individual patient circumstances.
    Original languageEnglish
    Pages (from-to)153-168
    Number of pages16
    JournalInternational Journal of Clinical Practice
    Volume58
    Issue number2
    DOIs
    Publication statusPublished - 2004

    Fingerprint

    Blood Vessels
    Primary Health Care
    Guidelines
    Platelet Aggregation Inhibitors
    Atherosclerotic Plaques
    Secondary Prevention
    Libraries
    Thrombosis
    Cardiovascular Diseases
    Ischemia
    Extremities
    Stroke
    Myocardial Infarction
    Therapeutics

    Cite this

    Betteridge, D J ; Belch, J ; Brown, M. M. ; Gent, M ; Julian, D ; Long, S ; Morris, S ; Pittard, J ; Pye, M. / Guidelines on the management of secondary prophylaxis of vascular events in stable patients in primary care. In: International Journal of Clinical Practice. 2004 ; Vol. 58, No. 2. pp. 153-168.
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    abstract = "Atherothrombosis, thrombus formation superimposed on an existing atherosclerotic plaque, is an acute process leading to ischaemic events such as myocardial infarction, stroke and critical limb ischaemia. Patients presenting with clinical conditions associated with atherothrombosis are at increased risk of subsequent vascular events. The beneficial effect of antiplatelet therapies for short-term and long-term secondary prevention of atherothrombotic events has been established. These guidelines aim to provide evidence-based recommendations that will assist in the antiplatelet-mediated secondary prophylaxis of vascular events in patients with stable cardiovascular disease treated in the primary healthcare setting. Medline and the Cochrane library were accessed using free-text strategies in the domains of antiplatelet agents and antithrombotics. Development of the guidelines was driven by a series of Steering Committee meetings, in which the quality of relevant studies was assessed and identified using narrative summary. These guidelines present evidence and recommendations for the treatment of numerous atherothrombotic indications depending on individual patient circumstances.",
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    Guidelines on the management of secondary prophylaxis of vascular events in stable patients in primary care. / Betteridge, D J; Belch, J; Brown, M. M.; Gent, M; Julian, D; Long, S; Morris, S; Pittard, J; Pye, M.

    In: International Journal of Clinical Practice, Vol. 58, No. 2, 2004, p. 153-168.

    Research output: Contribution to journalArticle

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