Has the epidemic of allergic contact dermatitis due to Methylisothiazolinone reached its peak?

Z. C. Venables; J. F. Bourke; D. A. Buckley; F. Campbell; M. M. U. Chowdhury; S. Abdul-Ghaffar; C. Green; C. R. Holden; J. McFadden; D. Orton; R. A. Sabroe; J. Sansom; N. M. Stone; S. H. Wakelin; S. M. Wilkinson; G. A. Johnston

doi:10.1111/bjd.15016

Has the epidemic of allergic contact dermatitis due to Methylisothiazolinone reached its peak?

Z. C. Venables, J. F. Bourke, D. A. Buckley, F. Campbell, M. M. U. Chowdhury, S. Abdul-Ghaffar, C. Green, C. R. Holden, J. McFadden, D. Orton, R. A. Sabroe, J. Sansom, N. M. Stone, S. H. Wakelin, S. M. Wilkinson, G. A. Johnston (Lead / Corresponding author)

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Abstract

Methylisothiazolinone (MI) is a preservative used in many household and industrial products. There has been an unprecedented global rise in allergic contact dermatitis (ACD) from its presence in personal care products (PCPs). In 2005 changes to EU legislation allowed MI, used in combination with methylchloroisothiazolinone (MCI), to be used at concentrations of up to 100ppm, 25 times higher than previously permitted. MI was also permitted to be used alone, whereas previously it was only used in combination with MCI in a 3:1 mix.(1) This resulted in the chain of events that led to the current MI allergy epidemic.By 2010, the first case series of ACD to MI as a cosmetic allergen was published. This article is protected by copyright. All rights reserved.

Original language	English
Pages (from-to)	276-278
Number of pages	3
Journal	British Journal of Dermatology
Volume	177
Issue number	1
Early online date	31 Aug 2016
DOIs	https://doi.org/10.1111/bjd.15016
Publication status	Published - 21 Jul 2017

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10.1111/bjd.15016

Author Accepted Manuscript
This is the peer reviewed version of the following article: 'Has the epidemic of allergic contact dermatitis due to Methylisothiazolinone reached its peak?', British Journal of Dermatology, which has been published in final form at http://dx.doi.org/10.1111/bjd.15016. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
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Cite this

Venables, Z. C., Bourke, J. F., Buckley, D. A., Campbell, F., Chowdhury, M. M. U., Abdul-Ghaffar, S., Green, C., Holden, C. R., McFadden, J., Orton, D., Sabroe, R. A., Sansom, J., Stone, N. M., Wakelin, S. H., Wilkinson, S. M., & Johnston, G. A. (2017). Has the epidemic of allergic contact dermatitis due to Methylisothiazolinone reached its peak? British Journal of Dermatology, 177(1), 276-278. https://doi.org/10.1111/bjd.15016

@article{42b2f5f430084a56b622cb019d835998,

title = "Has the epidemic of allergic contact dermatitis due to Methylisothiazolinone reached its peak?",

abstract = "Methylisothiazolinone (MI) is a preservative used in many household and industrial products. There has been an unprecedented global rise in allergic contact dermatitis (ACD) from its presence in personal care products (PCPs). In 2005 changes to EU legislation allowed MI, used in combination with methylchloroisothiazolinone (MCI), to be used at concentrations of up to 100ppm, 25 times higher than previously permitted. MI was also permitted to be used alone, whereas previously it was only used in combination with MCI in a 3:1 mix.(1) This resulted in the chain of events that led to the current MI allergy epidemic.By 2010, the first case series of ACD to MI as a cosmetic allergen was published. This article is protected by copyright. All rights reserved.",

author = "Venables, {Z. C.} and Bourke, {J. F.} and Buckley, {D. A.} and F. Campbell and Chowdhury, {M. M. U.} and S. Abdul-Ghaffar and C. Green and Holden, {C. R.} and J. McFadden and D. Orton and Sabroe, {R. A.} and J. Sansom and Stone, {N. M.} and Wakelin, {S. H.} and Wilkinson, {S. M.} and Johnston, {G. A.}",

year = "2017",

month = jul,

day = "21",

doi = "10.1111/bjd.15016",

language = "English",

volume = "177",

pages = "276--278",

journal = "British Journal of Dermatology",

issn = "0007-0963",

publisher = "Oxford University Press",