Heavy silicone oil tamponade: a multicentre experience

Max Davidson; Samir Dowlut; Jufen Zhang; Khayam Naderi; Teresa Sandinha; Megan Kay Wood; Matthew Schneiders; Shohista Saidkasimova; Shamfa Peart; Ray Chaudhuri; Manish Gunda; Manzar Saeed; Florian Heussen; Johannes Keller; Sonali Tarafdar; Aman Chandra

doi:10.1136/bmjophth-2022-001018

Heavy silicone oil tamponade: a multicentre experience

Max Davidson (Lead / Corresponding author), Samir Dowlut, Jufen Zhang, Khayam Naderi, Teresa Sandinha, Megan Kay Wood, Matthew Schneiders, Shohista Saidkasimova, Shamfa Peart, Ray Chaudhuri, Manish Gunda, Manzar Saeed, Florian Heussen, Johannes Keller, Sonali Tarafdar, Aman Chandra

Undergraduate Medicine

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

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Abstract

Objective: To report multicentred use of the heavy silicone oil Densiron 68 for anatomical reattachment following rhegmatogenous retinal detachment (RRD) repair and its associated complications.

Methods and analysis: Patients from seven vitreoretinal units within the UK that underwent RRD repair with Densiron 68 between January 2015 and December 2019 were identified. Primary outcome measures were primary and final reattachment rate, retained Densiron and failure rate. Secondary outcome measures were duration of tamponade, final visual acuity (VA) and complications of heavy silicone oil.

Results: 134 eyes of 134 patients were involved in the study. Primary surgical success was achieved in 48.5%, while a final reattachment rate of 73.4% was observed. The mean duration of Densiron 68 tamponade was 139.5 days. Mean final VA was 1.01 (range 0-2.9). 8 eyes (6.0%) required long-term topical steroids for anterior uveitis, whereas none of the eyes required long-term pressure-lowering treatment. Emulsification rate was 10.7% (6 eyes).

Conclusion: This is the largest real-world study on Densiron 68 in the UK. Densiron 68 facilitates tamponade of inferior retinal pathology and may be considered as an option for tamponade of inferior retinal pathologies.

Original language	English
Article number	e001018
Number of pages	6
Journal	BMJ Open Ophthalmology
Volume	7
Issue number	1
Early online date	8 Dec 2022
DOIs	https://doi.org/10.1136/bmjophth-2022-001018
Publication status	Published - 8 Dec 2022

Keywords

retina
treatment surgery

ASJC Scopus subject areas

Ophthalmology

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10.1136/bmjophth-2022-001018Licence: CC BY-NC

Final published versionFinal published version, 255 KBLicence: CC BY-NC

Cite this

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title = "Heavy silicone oil tamponade: a multicentre experience",

abstract = "Objective: To report multicentred use of the heavy silicone oil Densiron 68 for anatomical reattachment following rhegmatogenous retinal detachment (RRD) repair and its associated complications. Methods and analysis: Patients from seven vitreoretinal units within the UK that underwent RRD repair with Densiron 68 between January 2015 and December 2019 were identified. Primary outcome measures were primary and final reattachment rate, retained Densiron and failure rate. Secondary outcome measures were duration of tamponade, final visual acuity (VA) and complications of heavy silicone oil. Results: 134 eyes of 134 patients were involved in the study. Primary surgical success was achieved in 48.5%, while a final reattachment rate of 73.4% was observed. The mean duration of Densiron 68 tamponade was 139.5 days. Mean final VA was 1.01 (range 0-2.9). 8 eyes (6.0%) required long-term topical steroids for anterior uveitis, whereas none of the eyes required long-term pressure-lowering treatment. Emulsification rate was 10.7% (6 eyes). Conclusion: This is the largest real-world study on Densiron 68 in the UK. Densiron 68 facilitates tamponade of inferior retinal pathology and may be considered as an option for tamponade of inferior retinal pathologies.",

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AU - Dowlut, Samir

AU - Zhang, Jufen

AU - Naderi, Khayam

AU - Sandinha, Teresa

AU - Wood, Megan Kay

AU - Schneiders, Matthew

AU - Saidkasimova, Shohista

AU - Peart, Shamfa

AU - Chaudhuri, Ray

AU - Gunda, Manish

AU - Saeed, Manzar

AU - Heussen, Florian

AU - Keller, Johannes

AU - Tarafdar, Sonali

AU - Chandra, Aman

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N2 - Objective: To report multicentred use of the heavy silicone oil Densiron 68 for anatomical reattachment following rhegmatogenous retinal detachment (RRD) repair and its associated complications. Methods and analysis: Patients from seven vitreoretinal units within the UK that underwent RRD repair with Densiron 68 between January 2015 and December 2019 were identified. Primary outcome measures were primary and final reattachment rate, retained Densiron and failure rate. Secondary outcome measures were duration of tamponade, final visual acuity (VA) and complications of heavy silicone oil. Results: 134 eyes of 134 patients were involved in the study. Primary surgical success was achieved in 48.5%, while a final reattachment rate of 73.4% was observed. The mean duration of Densiron 68 tamponade was 139.5 days. Mean final VA was 1.01 (range 0-2.9). 8 eyes (6.0%) required long-term topical steroids for anterior uveitis, whereas none of the eyes required long-term pressure-lowering treatment. Emulsification rate was 10.7% (6 eyes). Conclusion: This is the largest real-world study on Densiron 68 in the UK. Densiron 68 facilitates tamponade of inferior retinal pathology and may be considered as an option for tamponade of inferior retinal pathologies.

AB - Objective: To report multicentred use of the heavy silicone oil Densiron 68 for anatomical reattachment following rhegmatogenous retinal detachment (RRD) repair and its associated complications. Methods and analysis: Patients from seven vitreoretinal units within the UK that underwent RRD repair with Densiron 68 between January 2015 and December 2019 were identified. Primary outcome measures were primary and final reattachment rate, retained Densiron and failure rate. Secondary outcome measures were duration of tamponade, final visual acuity (VA) and complications of heavy silicone oil. Results: 134 eyes of 134 patients were involved in the study. Primary surgical success was achieved in 48.5%, while a final reattachment rate of 73.4% was observed. The mean duration of Densiron 68 tamponade was 139.5 days. Mean final VA was 1.01 (range 0-2.9). 8 eyes (6.0%) required long-term topical steroids for anterior uveitis, whereas none of the eyes required long-term pressure-lowering treatment. Emulsification rate was 10.7% (6 eyes). Conclusion: This is the largest real-world study on Densiron 68 in the UK. Densiron 68 facilitates tamponade of inferior retinal pathology and may be considered as an option for tamponade of inferior retinal pathologies.

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Heavy silicone oil tamponade: a multicentre experience

Abstract

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