Hidradenoma masquerading digital ganglion cyst: a rare phenomenon

Navnit Makaram; Iskander H. Chaudhry; Makaram S. Srinivasan

doi:10.1016/j.amsu.2016.07.017

Hidradenoma masquerading digital ganglion cyst: a rare phenomenon

Navnit Makaram (Lead / Corresponding author), Iskander H. Chaudhry (Lead / Corresponding author), Makaram S. Srinivasan (Lead / Corresponding author)

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Abstract

INTRODUCTION: Mucous cyst is the commonest soft tissue tumor in the dorsum of the distal interphalangeal joint (DIPJ) of the finger. We report the first case of a recurring eccrine tumor (nodular hidradenoma), mimicking a mucous/ganglion cyst, on the dorsum of the DIPJ.

CASE REPORT: A 54 year old man presented with painless, hemispherical, colored swelling on the dorsum of his right middle finger (dominant hand), which appeared to have recurred from a previous surgery. The lesion was excised and operative findings from the medical notes showed the gross appearance to be a soft, white, glistening, smooth-surfaced, myxoid nodule resembling a "ganglion cyst". Immunohistochemistry showed the tumour to be positive for S100, smooth muscle actin and cytokeratin 7. Ductal differentiation was confirmed by staining for epithelial membrane antigen and carcinoembryonic antigen. The histological features were that of atypical and solid cystic hidradenoma.

DISCUSSION: This is the first reported case of this rare tumour presenting as mucous cyst. We conduct a review of the literature of nodular hidradenomas, illustrating the immunohistologic findings in this tumour to emphasise the atypical features.We emphasise the importance of considering hidradenoma in the differential diagnosis of such lesions of the finger, in view of its high recurrence rate and the possibility of malignant transformation.

Original language	English
Pages (from-to)	22-26
Number of pages	5
Journal	Annals of Medicine and Surgery
Volume	10
Early online date	22 Jul 2016
DOIs	https://doi.org/10.1016/j.amsu.2016.07.017
Publication status	Published - Sept 2016

Keywords

Hidradenoma
Ganglion cyst
Adnexal tumour
Eccrine
Hand

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10.1016/j.amsu.2016.07.017Licence: CC BY-NC-ND

Final Published Version
©2016 The Author(s). Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Final published version, 1.67 MBLicence: CC BY-NC-ND

Cite this

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title = "Hidradenoma masquerading digital ganglion cyst: a rare phenomenon",

abstract = "INTRODUCTION: Mucous cyst is the commonest soft tissue tumor in the dorsum of the distal interphalangeal joint (DIPJ) of the finger. We report the first case of a recurring eccrine tumor (nodular hidradenoma), mimicking a mucous/ganglion cyst, on the dorsum of the DIPJ.CASE REPORT: A 54 year old man presented with painless, hemispherical, colored swelling on the dorsum of his right middle finger (dominant hand), which appeared to have recurred from a previous surgery. The lesion was excised and operative findings from the medical notes showed the gross appearance to be a soft, white, glistening, smooth-surfaced, myxoid nodule resembling a {"}ganglion cyst{"}. Immunohistochemistry showed the tumour to be positive for S100, smooth muscle actin and cytokeratin 7. Ductal differentiation was confirmed by staining for epithelial membrane antigen and carcinoembryonic antigen. The histological features were that of atypical and solid cystic hidradenoma.DISCUSSION: This is the first reported case of this rare tumour presenting as mucous cyst. We conduct a review of the literature of nodular hidradenomas, illustrating the immunohistologic findings in this tumour to emphasise the atypical features.We emphasise the importance of considering hidradenoma in the differential diagnosis of such lesions of the finger, in view of its high recurrence rate and the possibility of malignant transformation.",

keywords = "Hidradenoma, Ganglion cyst, Adnexal tumour, Eccrine, Hand",

author = "Navnit Makaram and Chaudhry, {Iskander H.} and Srinivasan, {Makaram S.}",

year = "2016",

month = sep,

doi = "10.1016/j.amsu.2016.07.017",

language = "English",

volume = "10",

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journal = "Annals of Medicine and Surgery ",

issn = "2049-0801",

publisher = "Elsevier",

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TY - JOUR

T1 - Hidradenoma masquerading digital ganglion cyst

T2 - a rare phenomenon

AU - Makaram, Navnit

AU - Chaudhry, Iskander H.

AU - Srinivasan, Makaram S.

PY - 2016/9

Y1 - 2016/9

N2 - INTRODUCTION: Mucous cyst is the commonest soft tissue tumor in the dorsum of the distal interphalangeal joint (DIPJ) of the finger. We report the first case of a recurring eccrine tumor (nodular hidradenoma), mimicking a mucous/ganglion cyst, on the dorsum of the DIPJ.CASE REPORT: A 54 year old man presented with painless, hemispherical, colored swelling on the dorsum of his right middle finger (dominant hand), which appeared to have recurred from a previous surgery. The lesion was excised and operative findings from the medical notes showed the gross appearance to be a soft, white, glistening, smooth-surfaced, myxoid nodule resembling a "ganglion cyst". Immunohistochemistry showed the tumour to be positive for S100, smooth muscle actin and cytokeratin 7. Ductal differentiation was confirmed by staining for epithelial membrane antigen and carcinoembryonic antigen. The histological features were that of atypical and solid cystic hidradenoma.DISCUSSION: This is the first reported case of this rare tumour presenting as mucous cyst. We conduct a review of the literature of nodular hidradenomas, illustrating the immunohistologic findings in this tumour to emphasise the atypical features.We emphasise the importance of considering hidradenoma in the differential diagnosis of such lesions of the finger, in view of its high recurrence rate and the possibility of malignant transformation.

AB - INTRODUCTION: Mucous cyst is the commonest soft tissue tumor in the dorsum of the distal interphalangeal joint (DIPJ) of the finger. We report the first case of a recurring eccrine tumor (nodular hidradenoma), mimicking a mucous/ganglion cyst, on the dorsum of the DIPJ.CASE REPORT: A 54 year old man presented with painless, hemispherical, colored swelling on the dorsum of his right middle finger (dominant hand), which appeared to have recurred from a previous surgery. The lesion was excised and operative findings from the medical notes showed the gross appearance to be a soft, white, glistening, smooth-surfaced, myxoid nodule resembling a "ganglion cyst". Immunohistochemistry showed the tumour to be positive for S100, smooth muscle actin and cytokeratin 7. Ductal differentiation was confirmed by staining for epithelial membrane antigen and carcinoembryonic antigen. The histological features were that of atypical and solid cystic hidradenoma.DISCUSSION: This is the first reported case of this rare tumour presenting as mucous cyst. We conduct a review of the literature of nodular hidradenomas, illustrating the immunohistologic findings in this tumour to emphasise the atypical features.We emphasise the importance of considering hidradenoma in the differential diagnosis of such lesions of the finger, in view of its high recurrence rate and the possibility of malignant transformation.

KW - Hidradenoma

KW - Ganglion cyst

KW - Adnexal tumour

KW - Eccrine

KW - Hand

U2 - 10.1016/j.amsu.2016.07.017

DO - 10.1016/j.amsu.2016.07.017

M3 - Article

C2 - 27625783

SN - 2049-0801

VL - 10

SP - 22

EP - 26

JO - Annals of Medicine and Surgery

JF - Annals of Medicine and Surgery

ER -

Hidradenoma masquerading digital ganglion cyst: a rare phenomenon

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