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High affinity binding of epibatidine to serotonin type 3 receptors
Renaldo C. Drisdel
, Douglas Sharp
, Tricia N Henderson
,
Tim G. Hales
, William N. Green
Research output
:
Contribution to journal
›
Article
›
peer-review
29
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Citations (Scopus)
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Keyphrases
Epibatidine
100%
High-affinity Binding
100%
Serotonin Type 3 Receptor
100%
5-HT3R
75%
125I
41%
Mecamylamine
33%
5-hydroxytryptamine
25%
Nicotinic Acetylcholine Receptor (nAChR)
25%
Serotonin
16%
High Affinity
16%
Nicotine
16%
HEK Cells
16%
As(V)
8%
Binding Site
8%
Induced Current
8%
Rat Brain
8%
Non-competitive
8%
Central Nervous System
8%
Specific Ligands
8%
Peripheral Nervous System
8%
Competitive Inhibitor
8%
Neuroblastoma Cell Line
8%
Analgesic Properties
8%
N1E-115
8%
Brain Membranes
8%
5-HT3AR
8%
Ligand-specific
8%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Serotonin
100%
Epibatidine
100%
Iodine-125
41%
Mecamylamine
33%
Binding Site
8%
Nicotinic Receptor
8%
Analgesic Agent
8%
Neuroblastoma
8%
Competitive Inhibitor
8%
1 (3 Chlorophenyl)biguanide
8%
Biochemistry, Genetics and Molecular Biology
Binding Affinity
100%
Epibatidine
100%
Serotonin
100%
Iodine-125
41%
Mecamylamine
33%
Binding Site
8%
Agonist
8%
Nicotinic Acetylcholine Receptor
8%
Competitive Inhibition
8%