Projects per year
Abstract
The synthesis, photophysical and biological characterization of a small library of fluorescent 5-HT3 receptor ligands is described. Several of these novel granisetron conjugates have high quantum yields and show high affinity for the human 5-HT(3)AR. (C) 2011 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 1151-1155 |
Number of pages | 5 |
Journal | Bioorganic & Medicinal Chemistry Letters |
Volume | 22 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2012 |
Keywords
- 5-HT3 receptor
- Cys-loop ligand-gated ion channels
- Fluorescent ligands
- Radioligand binding
- In vivo imaging
- ANTAGONISTS
- TARGET
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Dive into the research topics of 'High-affinity fluorescent ligands for the 5-HT3 receptor'. Together they form a unique fingerprint.Projects
- 1 Finished
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Aref#d: 20481. The Mechanism of Action and Significance of RIC-3 A Selective Chaperone for Nicotinic and 5-HT3 Receptors
Connolly, C. (Investigator)
7/01/09 → 6/11/12
Project: Research