High yielding microbubble production method

TY - JOUR

T1 - High yielding microbubble production method

AU - Fiabane, Joe

AU - Prentice, Paul

AU - Pancholi, Ketan

PY - 2016

Y1 - 2016

N2 - Microfluidic approaches to microbubble production are generally disadvantaged by low yield and high susceptibility to (micro)channel blockages. This paper presents an alternative method of producing microbubbles of 2.6 m mean diameter at concentrations in excess of 30 × 106 mL-1. In this method, the nitrogen gas flowing inside the liquid jet is disintegrated into spray of microbubble when air surrounding this coflowing nitrogen gas-liquid jet passes through a 100 m orifice at high velocity. Resulting microbubble foam has the polydispersity index of 16%. Moreover, a ratio of mean microbubble diameter to channel width ratio was found to be less than 0.025, which substantially alleviates the occurrence of blockages during production.

AB - Microfluidic approaches to microbubble production are generally disadvantaged by low yield and high susceptibility to (micro)channel blockages. This paper presents an alternative method of producing microbubbles of 2.6 m mean diameter at concentrations in excess of 30 × 106 mL-1. In this method, the nitrogen gas flowing inside the liquid jet is disintegrated into spray of microbubble when air surrounding this coflowing nitrogen gas-liquid jet passes through a 100 m orifice at high velocity. Resulting microbubble foam has the polydispersity index of 16%. Moreover, a ratio of mean microbubble diameter to channel width ratio was found to be less than 0.025, which substantially alleviates the occurrence of blockages during production.

UR - https://www.scopus.com/pages/publications/84961863017

U2 - 10.1155/2016/3572827

DO - 10.1155/2016/3572827

M3 - Article

C2 - 27034935

AN - SCOPUS:84961863017

SN - 2314-6133

VL - 2016

JO - BioMed Research International

JF - BioMed Research International

M1 - 3572827

ER -