How common is hearing impairment in osteogenesis imperfecta?

C. R. Paterson (Lead / Corresponding author), E. A. Monk, S. J. McAllion

    Research output: Contribution to journalArticle

    41 Citations (Scopus)

    Abstract

    Hearing impairment has long been recognized as a common feature in osteogenesis imperfecta. The figures in some publications could be taken to imply that, with increasing age, the proportion of osteogenesis imperfecta patients with hearing impairment approaches 100 per cent. The incidence of hearing loss in a large survey of 1394 patients with osteogenesis imperfecta was examined. It was found that the most common age of onset was in the second, third and fourth decades of life. At the age of 50 approximately 50 per cent of the patients had symptoms of hearing impairment; over the next 20 years there was little further increase. Differences were shown between patients with different clinical types of osteogenesis imperfecta as delineated in the Sillence classification; hearing loss was significantly less common in the type IV disease than in the type I disorder. Among the 29 families with osteogenesis imperfecta type IA there were distinct differences in the likelihood of hearing loss. These findings provide insights which will be valuable in giving patients advice on the likelihood of developing hearing loss in the future.

    Original languageEnglish
    Pages (from-to)280-282
    Number of pages3
    JournalJournal of Laryngology and Otology
    Volume115
    Issue number4
    DOIs
    Publication statusPublished - Apr 2001

    Fingerprint

    Osteogenesis Imperfecta
    Hearing Loss
    Age of Onset
    Publications
    Incidence

    Keywords

    • Adolescent
    • Adult
    • Age of Onset
    • Aged
    • Aged, 80 and over
    • Child
    • Child, Preschool
    • Hearing Disorders/epidemiology
    • Humans
    • Incidence
    • Infant
    • Infant, Newborn
    • Middle Aged
    • Osteogenesis Imperfecta/complications
    • Pedigree
    • Phenotype

    Cite this

    Paterson, C. R. ; Monk, E. A. ; McAllion, S. J. / How common is hearing impairment in osteogenesis imperfecta?. In: Journal of Laryngology and Otology. 2001 ; Vol. 115, No. 4. pp. 280-282.
    @article{a8a76ffa10c74e79a1ff953b241e1f3d,
    title = "How common is hearing impairment in osteogenesis imperfecta?",
    abstract = "Hearing impairment has long been recognized as a common feature in osteogenesis imperfecta. The figures in some publications could be taken to imply that, with increasing age, the proportion of osteogenesis imperfecta patients with hearing impairment approaches 100 per cent. The incidence of hearing loss in a large survey of 1394 patients with osteogenesis imperfecta was examined. It was found that the most common age of onset was in the second, third and fourth decades of life. At the age of 50 approximately 50 per cent of the patients had symptoms of hearing impairment; over the next 20 years there was little further increase. Differences were shown between patients with different clinical types of osteogenesis imperfecta as delineated in the Sillence classification; hearing loss was significantly less common in the type IV disease than in the type I disorder. Among the 29 families with osteogenesis imperfecta type IA there were distinct differences in the likelihood of hearing loss. These findings provide insights which will be valuable in giving patients advice on the likelihood of developing hearing loss in the future.",
    keywords = "Adolescent, Adult, Age of Onset, Aged, Aged, 80 and over, Child, Child, Preschool, Hearing Disorders/epidemiology, Humans, Incidence, Infant, Infant, Newborn, Middle Aged, Osteogenesis Imperfecta/complications, Pedigree, Phenotype",
    author = "Paterson, {C. R.} and Monk, {E. A.} and McAllion, {S. J.}",
    year = "2001",
    month = "4",
    doi = "10.1258/0022215011907442",
    language = "English",
    volume = "115",
    pages = "280--282",
    journal = "Journal of Laryngology and Otology",
    issn = "0022-2151",
    publisher = "Cambridge University Press",
    number = "4",

    }

    How common is hearing impairment in osteogenesis imperfecta? / Paterson, C. R. (Lead / Corresponding author); Monk, E. A.; McAllion, S. J.

    In: Journal of Laryngology and Otology, Vol. 115, No. 4, 04.2001, p. 280-282.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - How common is hearing impairment in osteogenesis imperfecta?

    AU - Paterson, C. R.

    AU - Monk, E. A.

    AU - McAllion, S. J.

    PY - 2001/4

    Y1 - 2001/4

    N2 - Hearing impairment has long been recognized as a common feature in osteogenesis imperfecta. The figures in some publications could be taken to imply that, with increasing age, the proportion of osteogenesis imperfecta patients with hearing impairment approaches 100 per cent. The incidence of hearing loss in a large survey of 1394 patients with osteogenesis imperfecta was examined. It was found that the most common age of onset was in the second, third and fourth decades of life. At the age of 50 approximately 50 per cent of the patients had symptoms of hearing impairment; over the next 20 years there was little further increase. Differences were shown between patients with different clinical types of osteogenesis imperfecta as delineated in the Sillence classification; hearing loss was significantly less common in the type IV disease than in the type I disorder. Among the 29 families with osteogenesis imperfecta type IA there were distinct differences in the likelihood of hearing loss. These findings provide insights which will be valuable in giving patients advice on the likelihood of developing hearing loss in the future.

    AB - Hearing impairment has long been recognized as a common feature in osteogenesis imperfecta. The figures in some publications could be taken to imply that, with increasing age, the proportion of osteogenesis imperfecta patients with hearing impairment approaches 100 per cent. The incidence of hearing loss in a large survey of 1394 patients with osteogenesis imperfecta was examined. It was found that the most common age of onset was in the second, third and fourth decades of life. At the age of 50 approximately 50 per cent of the patients had symptoms of hearing impairment; over the next 20 years there was little further increase. Differences were shown between patients with different clinical types of osteogenesis imperfecta as delineated in the Sillence classification; hearing loss was significantly less common in the type IV disease than in the type I disorder. Among the 29 families with osteogenesis imperfecta type IA there were distinct differences in the likelihood of hearing loss. These findings provide insights which will be valuable in giving patients advice on the likelihood of developing hearing loss in the future.

    KW - Adolescent

    KW - Adult

    KW - Age of Onset

    KW - Aged

    KW - Aged, 80 and over

    KW - Child

    KW - Child, Preschool

    KW - Hearing Disorders/epidemiology

    KW - Humans

    KW - Incidence

    KW - Infant

    KW - Infant, Newborn

    KW - Middle Aged

    KW - Osteogenesis Imperfecta/complications

    KW - Pedigree

    KW - Phenotype

    U2 - 10.1258/0022215011907442

    DO - 10.1258/0022215011907442

    M3 - Article

    C2 - 11276328

    VL - 115

    SP - 280

    EP - 282

    JO - Journal of Laryngology and Otology

    JF - Journal of Laryngology and Otology

    SN - 0022-2151

    IS - 4

    ER -