Professionalism has been increasingly recognised as an explicit component of medical education, especially in the western world. Professionalism is culture-sensitive. Few efforts have been made to conceptualise professionalism in relation to the Arabian context. The aim of this study is to validate the components of professionalism framework of the American Board of Internal Medicine (ABIM) to the Arabian context. The authors invited a heterogeneous group of native Arab health professionals and academics to contribute to a reference panel. They represented a variety of disciplines, and seniority levels, and from different healthcare institutions and medical schools in Egypt, Saudi Arabia and United Arab Emirates. They were queried about their perception of the importance of each domain of professionalism as proposed by the ABIM, and were encouraged to suggest new domains if they thought it necessary. Thirty two out of the 45 invited health professionals and educators (71%) contributed to the reference panel. The panel confirmed the appropriateness of the six ABIM domains to the Arabian context, and further proposed the Autonomy of professionals as an additional domain. The modified framework, based on ABIM domains, demonstrated the Arabian conceptualisation of professionalism.