How RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes

David M. J. Lilley (Lead / Corresponding author)

Research output: Contribution to journalReview article

18 Citations (Scopus)
808 Downloads (Pure)

Abstract

Recent structural and mechanistic studies have shed considerable light on the catalytic mechanisms of nucleolytic ribozymes. The discovery of several new ribozymes in this class has now allowed comparisons to be made, and the beginnings of mechanistic groupings to emerge.

Original languageEnglish
Pages (from-to)683-691
Number of pages9
JournalBiochemical Society Transactions
Volume45
Issue number3
DOIs
Publication statusPublished - 15 Jun 2017

Keywords

  • HDV
  • Hepatitis delta virus
  • Quantum mechanical/molecular mechanical
  • Varkud satellite

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