How robust is the ligand binding transition state?

Keyphrases

• Ligand Binding 100%
• Transition State 100%
• Residence Time 50%
• Soluble Epoxide Hydrolase 33%
• Transition State Ensemble 33%
• Spatial Location 16%
• Computational Model 16%
• Degrees of Freedom 16%
• Order of Magnitude 16%
• Similarity Structure 16%
• Specificity Protein 1 16%
• Drug Target 16%
• Free Energy 16%
• Bound States 16%
• Drug Efficacy 16%
• Molecular Dynamics 16%
• Directly Observed 16%
• Binding Pathway 16%
• Drug Design 16%
• Protein Residue 16%
• Structural Details 16%
• Drug Binding 16%
• Enhanced Sampling 16%
• Short Lifetime 16%
• Predictive Computational Model 16%
• Thermodynamic Quantities 16%

Biochemistry, Genetics and Molecular Biology

• Ligand Binding 100%
• Retention Time 60%
• Epoxide Hydrolase 40%
• Dynamics 20%
• Lifespan 20%
• Drug Efficacy 20%
• Drug Binding 20%