How to be a mitotic chromosome

Sandra C. Moser; Jason R. Swedlow

doi:10.1007/s10577-011-9198-3

How to be a mitotic chromosome

Sandra C. Moser, Jason R. Swedlow

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Proper mitotic chromosome structure is essential for faithful chromosome segregation. Mounting evidence suggests that mitotic chromosome assembly is a progressive, dynamic process that requires topoisomerase II, condensins and cohesin and the activity of several signalling molecules. Current results suggest how these different activities might interact to achieve the familiar form of the mitotic chromosome.

Original language	English
Pages (from-to)	307-319
Number of pages	13
Journal	Chromosome Research
Volume	19
Issue number	3
DOIs	https://doi.org/10.1007/s10577-011-9198-3
Publication status	Published - Apr 2011

Keywords

chromosome structure
condensation
condensin
topoisomerase II
cohesin
DNA TOPOISOMERASE-II
SISTER-CHROMATID RESOLUTION
HISTONE H3 PHOSPHORYLATION
CELL-CYCLE PROGRESSION
CONDENSATION IN-VITRO
AURORA-B KINASE
METAPHASE CHROMOSOME
SACCHAROMYCES-CEREVISIAE
FISSION YEAST
COHESIN REMOVAL

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title = "How to be a mitotic chromosome",

abstract = "Proper mitotic chromosome structure is essential for faithful chromosome segregation. Mounting evidence suggests that mitotic chromosome assembly is a progressive, dynamic process that requires topoisomerase II, condensins and cohesin and the activity of several signalling molecules. Current results suggest how these different activities might interact to achieve the familiar form of the mitotic chromosome.",

keywords = "chromosome structure, condensation, condensin, topoisomerase II, cohesin, DNA TOPOISOMERASE-II, SISTER-CHROMATID RESOLUTION, HISTONE H3 PHOSPHORYLATION, CELL-CYCLE PROGRESSION, CONDENSATION IN-VITRO, AURORA-B KINASE, METAPHASE CHROMOSOME, SACCHAROMYCES-CEREVISIAE, FISSION YEAST, COHESIN REMOVAL",

author = "Moser, {Sandra C.} and Swedlow, {Jason R.}",

year = "2011",

month = apr,

doi = "10.1007/s10577-011-9198-3",

language = "English",

volume = "19",

pages = "307--319",

journal = "Chromosome Research",

issn = "0967-3849",

publisher = "Springer Nature",

number = "3",

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TY - JOUR

T1 - How to be a mitotic chromosome

AU - Moser, Sandra C.

AU - Swedlow, Jason R.

PY - 2011/4

Y1 - 2011/4

N2 - Proper mitotic chromosome structure is essential for faithful chromosome segregation. Mounting evidence suggests that mitotic chromosome assembly is a progressive, dynamic process that requires topoisomerase II, condensins and cohesin and the activity of several signalling molecules. Current results suggest how these different activities might interact to achieve the familiar form of the mitotic chromosome.

AB - Proper mitotic chromosome structure is essential for faithful chromosome segregation. Mounting evidence suggests that mitotic chromosome assembly is a progressive, dynamic process that requires topoisomerase II, condensins and cohesin and the activity of several signalling molecules. Current results suggest how these different activities might interact to achieve the familiar form of the mitotic chromosome.

KW - chromosome structure

KW - condensation

KW - condensin

KW - topoisomerase II

KW - cohesin

KW - DNA TOPOISOMERASE-II

KW - SISTER-CHROMATID RESOLUTION

KW - HISTONE H3 PHOSPHORYLATION

KW - CELL-CYCLE PROGRESSION

KW - CONDENSATION IN-VITRO

KW - AURORA-B KINASE

KW - METAPHASE CHROMOSOME

KW - SACCHAROMYCES-CEREVISIAE

KW - FISSION YEAST

KW - COHESIN REMOVAL

U2 - 10.1007/s10577-011-9198-3

DO - 10.1007/s10577-011-9198-3

M3 - Article

C2 - 21461697

SN - 0967-3849

VL - 19

SP - 307

EP - 319

JO - Chromosome Research

JF - Chromosome Research

IS - 3

ER -

How to be a mitotic chromosome

Abstract

Keywords

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