How to convert host plants into nonhosts

Hazel McLellan; Petra C. Boevink; Paul R. J. Birch

doi:10.1016/j.tplants.2023.05.008

How to convert host plants into nonhosts

Hazel McLellan, Petra C. Boevink, Paul R. J. Birch (Lead / Corresponding author)

Plant Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

53 Downloads (Pure)

Abstract

Recent research demonstrates that undermining interactions between pathogen effectors and their host target proteins can reduce infection. As more effector–target pairs are identified, their structures and interaction surfaces exposed, and there is the possibility of making multiple edits to diverse plant genomes, the desire to convert crops to nonhosts could become reality.

Original language	English
Pages (from-to)	876-879
Number of pages	4
Journal	Trends in Plant Science
Volume	28
Issue number	8
Early online date	2 Jun 2023
DOIs	https://doi.org/10.1016/j.tplants.2023.05.008
Publication status	Published - Aug 2023

Keywords

AlphaFold2
CRISPR
disease
effector-targeted susceptibility
gene editing
immunity

ASJC Scopus subject areas

Plant Science

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10.1016/j.tplants.2023.05.008Licence: CC BY

Final Published VersionFinal published version, 795 KBLicence: CC BY

Cite this

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title = "How to convert host plants into nonhosts",

abstract = "Recent research demonstrates that undermining interactions between pathogen effectors and their host target proteins can reduce infection. As more effector–target pairs are identified, their structures and interaction surfaces exposed, and there is the possibility of making multiple edits to diverse plant genomes, the desire to convert crops to nonhosts could become reality.",

keywords = "AlphaFold2, CRISPR, disease, effector-targeted susceptibility, gene editing, immunity",

author = "Hazel McLellan and Boevink, {Petra C.} and Birch, {Paul R. J.}",

note = "Funding Information: P.R.J.B., H.M., and P.C.B are supported by the Biotechnology and Biological Sciences Research Council grant BB/S003096/1; European Research Council (ERC)-Advanced grant PathEVome (787764); and Scottish Government Rural and Environment Science and Analytical Services Division (RESAS). Copyright: Crown Copyright {\textcopyright} 2023 Published by Elsevier Ltd.",

year = "2023",

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language = "English",

volume = "28",

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issn = "1360-1385",

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T1 - How to convert host plants into nonhosts

AU - McLellan, Hazel

AU - Boevink, Petra C.

AU - Birch, Paul R. J.

N1 - Funding Information: P.R.J.B., H.M., and P.C.B are supported by the Biotechnology and Biological Sciences Research Council grant BB/S003096/1; European Research Council (ERC)-Advanced grant PathEVome (787764); and Scottish Government Rural and Environment Science and Analytical Services Division (RESAS). Copyright: Crown Copyright © 2023 Published by Elsevier Ltd.

PY - 2023/8

Y1 - 2023/8

N2 - Recent research demonstrates that undermining interactions between pathogen effectors and their host target proteins can reduce infection. As more effector–target pairs are identified, their structures and interaction surfaces exposed, and there is the possibility of making multiple edits to diverse plant genomes, the desire to convert crops to nonhosts could become reality.

AB - Recent research demonstrates that undermining interactions between pathogen effectors and their host target proteins can reduce infection. As more effector–target pairs are identified, their structures and interaction surfaces exposed, and there is the possibility of making multiple edits to diverse plant genomes, the desire to convert crops to nonhosts could become reality.

KW - AlphaFold2

KW - CRISPR

KW - disease

KW - effector-targeted susceptibility

KW - gene editing

KW - immunity

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U2 - 10.1016/j.tplants.2023.05.008

DO - 10.1016/j.tplants.2023.05.008

M3 - Article

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SN - 1360-1385

VL - 28

SP - 876

EP - 879

JO - Trends in Plant Science

JF - Trends in Plant Science

IS - 8

ER -

How to convert host plants into nonhosts

Abstract

Keywords

ASJC Scopus subject areas

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Do Pathogen Exracellular Vesicles Deliver Crop Disease: PathEVome

The Roles of Extracellular Vesicle Transport in Late Blight Disease Development (Industrial Partnership Award (IPA))

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How to convert host plants into nonhosts

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Projects

Do Pathogen Exracellular Vesicles Deliver Crop Disease: PathEVome

The Roles of Extracellular Vesicle Transport in Late Blight Disease Development (Industrial Partnership Award (IPA))

Cite this