Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation

Keyphrases

• Ionizing Radiation 100%
• Ataxia Telangiectasia mutated 100%
• Cell Resistance 100%
• 53BP1 66%
• Amino Acids 33%
• BRCT Domain 33%
• Genome Stability 33%
• Radiation Effects 33%
• Radiation-induced DNA Damage 16%
• Complementary DNA (cDNA) 16%
• Protein-protein Interaction 16%
• Cyclin-dependent Kinase Inhibitor p21 16%
• Protein Kinase 16%
• Small Interfering RNA (siRNA) 16%
• Phosphorylation 16%
• Interacting Proteins 16%
• DNA Damage 16%
• Cellular Sensitivity 16%
• Focus Formation 16%
• Deletion Analysis 16%
• Activation Domain 16%
• Molecular Role 16%
• Ataxia Telangiectasia 16%

Biochemistry, Genetics and Molecular Biology

• Ataxia Telangiectasia Mutated 100%
• P53 100%
• Amino Acids 40%
• BRCT Domain 40%
• Genome Instability 40%
• Cyclin-Dependent Kinase 20%
• P21 20%
• Protein Kinases 20%
• Small Interfering RNA 20%
• Transactivation 20%
• DNA Damage 20%
• Upregulation 20%
• Protein-Protein Interaction 20%
• Essential Gene 20%

Immunology and Microbiology

• Ataxia Telangiectasia 100%
• P53 100%
• Genomic Instability 33%
• Amino Acid 33%
• Transactivation 16%
• DNA Damage 16%
• Upregulation 16%
• Essential Gene 16%
• Cycline 16%
• Protein Protein Interaction 16%
• Peptides 16%