Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance

Joanna Burns, Stephen G. Ball, Gillian Worthy, Allan D. Struthers, David A. S. G. Mary, John P. Greenwood

    Research output: Contribution to journalArticle

    20 Citations (Scopus)

    Abstract

    Neuroendocrine activation may be an important adjunctive mechanism for left ventricular hypertrophy (LVH) development. Controversy exists to as to whether LVH regression occurs due to blood pressure (BP) reduction alone or if adjunctive mechanisms play a role. We planned to test the hypothesis that for a similar BP reduction, LVH regression would be greater using a drug combination selected specifically to reduce neuroendocrine activity compared with one that did not.
    Original languageEnglish
    Pages (from-to)2039-46
    Number of pages8
    JournalJournal of Hypertension
    Volume30
    Issue number10
    DOIs
    Publication statusPublished - Oct 2012

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