Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance

Joanna Burns; Stephen G. Ball; Gillian Worthy; Allan D. Struthers; David A. S. G. Mary; John P. Greenwood

doi:10.1097/HJH.0b013e328356b850

Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance

Joanna Burns, Stephen G. Ball, Gillian Worthy, Allan D. Struthers, David A. S. G. Mary, John P. Greenwood

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Neuroendocrine activation may be an important adjunctive mechanism for left ventricular hypertrophy (LVH) development. Controversy exists to as to whether LVH regression occurs due to blood pressure (BP) reduction alone or if adjunctive mechanisms play a role. We planned to test the hypothesis that for a similar BP reduction, LVH regression would be greater using a drug combination selected specifically to reduce neuroendocrine activity compared with one that did not.

Original language	English
Pages (from-to)	2039-46
Number of pages	8
Journal	Journal of Hypertension
Volume	30
Issue number	10
DOIs	https://doi.org/10.1097/HJH.0b013e328356b850
Publication status	Published - Oct 2012

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abstract = "Neuroendocrine activation may be an important adjunctive mechanism for left ventricular hypertrophy (LVH) development. Controversy exists to as to whether LVH regression occurs due to blood pressure (BP) reduction alone or if adjunctive mechanisms play a role. We planned to test the hypothesis that for a similar BP reduction, LVH regression would be greater using a drug combination selected specifically to reduce neuroendocrine activity compared with one that did not.",

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AU - Mary, David A. S. G.

AU - Greenwood, John P.

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Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance

Abstract

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