Abstract
Background: Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders.
Summary: The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management.
Key Messages: Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination.
Original language | English |
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Pages (from-to) | 290-298 |
Number of pages | 9 |
Journal | Digestive Diseases |
Volume | 40 |
Issue number | 3 |
Early online date | 25 May 2021 |
DOIs | |
Publication status | Published - May 2022 |
Keywords
- hyposplenism
- spleen
- coeliac disease
- inflammatory bowel disease
- Hyposplenism
- Inflammatory bowel disease
- Spleen
- Coeliac disease
ASJC Scopus subject areas
- Gastroenterology