Background: Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders.
Summary: The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management.
Key Messages: Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination.
|Number of pages||9|
|Early online date||25 May 2021|
|Publication status||Published - May 2022|
- coeliac disease
- inflammatory bowel disease
- Inflammatory bowel disease
- Coeliac disease
ASJC Scopus subject areas