The Seventh School Curriculum Reform in Korea was introduced in 2000 to prepare school-aged Koreans for an information and knowledge-based society. The reform effort emphasises information and communication technology (ICT) in the K-12 curriculum and a learner-centred pedagogy. This study examines the contributions of ICT, specifically, computer-assisted instruction (CAI), in Korean science classrooms. A sample of 234 Korean middle school students was categorised into five achievement groups. Data were collected from pre- and post-achievement test scores and pre- and post-questionnaires for attitudes toward science, future courses, and career aspirations in science. Findings include: (1) the lowest achievement group showed the most significant improvement after CAI (p=.000); (2) an improvement in student achievement in science significantly influenced students' attitudes toward science (p=.019), future course selections, and career aspirations related to science (p=.000); and (3) boys tended to perform better with CAI than girls. This research provides evidence that CAI has the potential to help lower achieving students in Korean science classes and may encourage enrolment in science.