Identification and Evaluation of dibasic piperidines as cell wall inhibitors against Mycobacterium tuberculosis

Claire Naylor; Gareth Prosser; Tracy Bayliss; Lila Berle; Joshua B Wallach; Heather Kim; Helena I.M. Boshoff; Rodrigo Aguilera Olvera; Ruth Casanueva; Stephen Thompson; Simon Green; Laura Guijarro-Lopez; Thomas R. Ioerger; Paul G. Wyatt; Kevin Read; Dirk Schnappinger; Clifton E Barry; Laura Simpson; Laura Cleghorn

doi:10.1021/acsinfecdis.6c00123

Identification and Evaluation of dibasic piperidines as cell wall inhibitors against Mycobacterium tuberculosis

Claire Naylor
, Gareth Prosser
, Tracy Bayliss
, Lila Berle
, Joshua B Wallach
, Heather Kim
, Helena I.M. Boshoff
, Rodrigo Aguilera Olvera
, Ruth Casanueva
, Stephen Thompson
, Simon Green
, Laura Guijarro-Lopez
, Thomas R. Ioerger
, Paul G. Wyatt
, Kevin Read
, Dirk Schnappinger
, Clifton E Barry
, Laura Simpson
, Laura Cleghorn (Lead / Corresponding author)

Drug Discovery Unit

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	ACS Infectious Diseases
DOIs	https://doi.org/10.1021/acsinfecdis.6c00123
Publication status	Published - 14 May 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1021/acsinfecdis.6c00123Licence: CC BY

Cite this

Naylor, C., Prosser, G., Bayliss, T., Berle, L., Wallach, J. B., Kim, H., Boshoff, H. I. M., Aguilera Olvera, R., Casanueva, R., Thompson, S., Green, S., Guijarro-Lopez, L., Ioerger, T. R., Wyatt, P. G., Read, K., Schnappinger, D., Barry, C. E., Simpson, L., & Cleghorn, L. (2026). Identification and Evaluation of dibasic piperidines as cell wall inhibitors against Mycobacterium tuberculosis. ACS Infectious Diseases. https://doi.org/10.1021/acsinfecdis.6c00123

@article{bb3864cdfe1f4405b55153129255ea1e,

title = "Identification and Evaluation of dibasic piperidines as cell wall inhibitors against Mycobacterium tuberculosis",

author = "Claire Naylor and Gareth Prosser and Tracy Bayliss and Lila Berle and Wallach, \{Joshua B\} and Heather Kim and Boshoff, \{Helena I.M.\} and \{Aguilera Olvera\}, Rodrigo and Ruth Casanueva and Stephen Thompson and Simon Green and Laura Guijarro-Lopez and Ioerger, \{Thomas R.\} and Wyatt, \{Paul G.\} and Kevin Read and Dirk Schnappinger and Barry, \{Clifton E\} and Laura Simpson and Laura Cleghorn",

year = "2026",

month = may,

day = "14",

doi = "10.1021/acsinfecdis.6c00123",

language = "English",

journal = "ACS Infectious Diseases",

issn = "2373-8227",

publisher = "American Chemical Society",

}

Naylor, C, Prosser, G, Bayliss, T, Berle, L, Wallach, JB, Kim, H, Boshoff, HIM, Aguilera Olvera, R, Casanueva, R, Thompson, S , Green, S, Guijarro-Lopez, L, Ioerger, TR, Wyatt, PG, Read, K, Schnappinger, D, Barry, CE, Simpson, L & Cleghorn, L 2026, 'Identification and Evaluation of dibasic piperidines as cell wall inhibitors against Mycobacterium tuberculosis', ACS Infectious Diseases. https://doi.org/10.1021/acsinfecdis.6c00123

TY - JOUR

T1 - Identification and Evaluation of dibasic piperidines as cell wall inhibitors against Mycobacterium tuberculosis

AU - Naylor, Claire

AU - Prosser, Gareth

AU - Bayliss, Tracy

AU - Berle, Lila

AU - Wallach, Joshua B

AU - Kim, Heather

AU - Boshoff, Helena I.M.

AU - Aguilera Olvera, Rodrigo

AU - Casanueva, Ruth

AU - Thompson, Stephen

AU - Green, Simon

AU - Guijarro-Lopez, Laura

AU - Ioerger, Thomas R.

AU - Wyatt, Paul G.

AU - Read, Kevin

AU - Schnappinger, Dirk

AU - Barry, Clifton E

AU - Simpson, Laura

AU - Cleghorn, Laura

PY - 2026/5/14

Y1 - 2026/5/14

U2 - 10.1021/acsinfecdis.6c00123

DO - 10.1021/acsinfecdis.6c00123

M3 - Article

SN - 2373-8227

JO - ACS Infectious Diseases

JF - ACS Infectious Diseases

ER -