Identification and Validation of Compounds Targeting Leishmania major Leucyl-Aminopeptidase M17

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  A Platform for Drug Target Deconvolution and Exploitation

  Gilbert, I. (Investigator), Horn, D. (Investigator), Pawlowic, M. C. (Investigator), Wyatt, P. (Investigator) & Wyllie, S. (Investigator)

  31/12/20 → 30/05/25

  Project: Research

  • Chagas Disease 100%
  • LysR Family 74%
  • Visceral Leishmaniasis 66%
  • Leishmania Donovani 64%
  • Drug Discovery 62%

• A Systems Approach for Understanding Cell Surface Dynamics in Trypanosomes (Investigator Award)

  Field, M. (Investigator)

  1/10/17 → 31/03/24

  Project: Research

  • Trypanosoma 100%
  • Trypanosome 90%
  • Eukaryotes 48%
  • Lineages 46%
  • Eukaryote 45%

• Wellcome Centre for Anti-Infectives Research

  Baragana, B. (Investigator), Cook, S. (Investigator), De Rycker, M. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator), Lee, M. (Investigator), Pawlowic, M. C. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & Wyllie, S. (Investigator)

  1/04/17 → 1/04/25

  Project: Research

  • Drug Discovery 100%
  • Trypanosoma Cruzi (T. cruzi) 88%
  • Chagas Disease 71%
  • Trypanosoma Cruzi 69%
  • Visceral Leishmaniasis 57%