Identification of a third form of protein phosphatase 1 in rabbit skeletal muscle that is associated with myosin

TY - JOUR

T1 - Identification of a third form of protein phosphatase 1 in rabbit skeletal muscle that is associated with myosin

AU - Chisholm, Alexander A K

AU - Cohen, Philip

PY - 1988/3/11

Y1 - 1988/3/11

N2 - A third form of protein phosphatase 1 has been identified in skeletal muscle which is distinct from the species composed of the catalytic subunit complexed to the glycogen-binding subunit (protein phosphatase 1G) or inhibitor-2 (protein phosphatase 1I). The third form has an apparent molecular mass of 110 kDa, is not immunoprecipitated by antibody prepared against the glycogen-binding subunit, does not interact with glycogen and is devoid of inhibitor-2. It is tightly bound to myosin and is therefore termed protein phosphatase 1M.

AB - A third form of protein phosphatase 1 has been identified in skeletal muscle which is distinct from the species composed of the catalytic subunit complexed to the glycogen-binding subunit (protein phosphatase 1G) or inhibitor-2 (protein phosphatase 1I). The third form has an apparent molecular mass of 110 kDa, is not immunoprecipitated by antibody prepared against the glycogen-binding subunit, does not interact with glycogen and is devoid of inhibitor-2. It is tightly bound to myosin and is therefore termed protein phosphatase 1M.

KW - (Skeletal muscle)

KW - Glycogen binding

KW - Glycogen metabolism

KW - Myosin binding

KW - Protein phosphatase 1

UR - https://www.scopus.com/pages/publications/0023878243

U2 - 10.1016/0167-4889(88)90032-8

DO - 10.1016/0167-4889(88)90032-8

M3 - Article

C2 - 2830909

AN - SCOPUS:0023878243

SN - 0167-4889

VL - 968

SP - 392

EP - 400

JO - BBA - Molecular Cell Research

JF - BBA - Molecular Cell Research

IS - 3

ER -