Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design

Paul G. Wyatt, Andrew J. Woodhead (Lead / Corresponding author), Valerio Berdini, John A. Boulstridge, Maria G. Carr, David M. Cross, Deborah J. Davis, Lindsay A. Devine, Theresa R. Early, Ruth E. Feltell, E. Jonathan Lewis, Rachel L. McMenamin, Eva F. Navarro, Michael A. O'Brien, Marc O'Reilly, Matthias Reule, Gordon Saxty, Lisa C. A. Seavers, Donna-Michelle Smith, Matt S. SquiresGary Trewartha, Margaret T. Walker, Alison J. -A. Woolford

    Research output: Contribution to journalArticlepeer-review

    331 Citations (Scopus)

    Fingerprint

    Dive into the research topics of 'Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design'. Together they form a unique fingerprint.

    Keyphrases

    Pharmacology, Toxicology and Pharmaceutical Science

    Biochemistry, Genetics and Molecular Biology